Correlation Between Perioperative Pain and Delirium in Geriatric Patients With Hip Fracture
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- pain score 30 minutes after fascia iliaca block
研究概览
简要总结
The objective of this trial will be to establish whether the ultrasound-guided suprainguinal fascia iliaca compartment block is capable of protecting geriatric patients with hip fracture from delirium as compared to placebo
详细描述
Geriatric patients suffer from hip fractures very often. Delirium is a perioperative neuropsychiatric complication that is characterized by sudden change of mental status, inattention, disorientation and memory impairment with fluctuations of symptoms during the day. Delirium causes increased morbidity and mortality, decreased postoperative functional activity and may predispose to dementia.
Perioperative pain may be an important predisposing factor to delirium. Intravenous opioids have been widely used to relieve patients with hip fracture from pain, but they have a lot of complications and have been correlated with delirium as well. Fascia Iliaca compartment block is a peripheral compartment nerve block that is used in hip surgeries. Use of this compartment nerve block to protect geriatric patients from delirium has not been studied.
The objective of this trial will be to establish whether the ultrasound-guided suprainguinal fascia iliaca compartment block is capable of protecting geriatric patients with hip fracture from delirium as compared to placebo
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 75 Years 至 105 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •geriatric patients
- •American Society of Anesthesiologists (ASA) I-III
- •hip fracture patients
排除标准
- •communication or language barriers
- •patients with nutritional problems
- •bedridden patients
结局指标
主要结局
pain score 30 minutes after fascia iliaca block
时间窗: 30 minutes after performance of fascia iliaca block
pain score by the use of Numeric Rating Scale (NRS) 30 minutes after fascia ilaca block, ranging from 0 to 10, where 0 means "no pain" and 10 means "worst pain imaginable"
pain score 12 hours after fascia iliaca block
时间窗: 12 hours after performance of fascia iliaca block
pain score by the use of Numeric Rating Scale (NRS) 12 hours after fascia ilaca block, ranging from 0 to 10, where 0 means "no pain" and 10 means "worst pain imaginable"
次要结局
- pain score 1-8 days after fascia iliaca block(1-8 days after fascia iliaca block)
研究者
Dr Kassiani Theodoraki
Professor of Anesthesiology
Aretaieion University Hospital