Speech Therapy in the Management of Chronic Cough

Not Applicable

Completed

• Conditions: Cough; Speech Therapy

• Registration Number: NCT03457610
• Lead Sponsor: Medical University of Warsaw

Brief Summary

Speech and language intervention (speech therapy) is one of the few methods which seem to be useful in management of persistent chronic cough. This method has not been available for patients with cough in Poland so far.The aim of the study is to implement speech therapy to the management plan of patients with difficult-to-treat chronic cough and to analyze its efficacy in this particular group.

Patients with difficult-to treat chronic cough will be offered speech and language intervention as an added therapy. The effectiveness of speech therapy will be measured by changes in cough severity, its influence on quality of life and cough challenge test before and after speech therapy measured in every patient.

Detailed Description

The efficacy of management of chronic cough in adults is limited. Speech and language intervention (speech therapy) is one of the few methods which seem to be useful in management of persistent chronic cough. This method has not been available for patients with cough in Poland so far.

The aim of the study is to implement speech therapy to the management plan of patients with difficult-to-treat chronic cough and to analyze its efficacy in this particular group.

Patients, who are diagnosed and unsuccessfully managed because of difficult-to treat chronic cough, will be offered speech and language intervention as an added therapy. It is based on the technique described by Vertigan et al.The entire therapy will consist of eight sessions once a week.

Cough severity, its influence on quality of life and cough challenge test with capsaicin will be assessed by Visual Analogue Scale, Leicester Cough Questionnaire and cough challenge test with capsaicin will be performed before and after speech therapy in every patient to analyze its effectiveness

Study Timeline

• Study Start: 2016-01-01
• Study First Submitted: 2018-03-01
• Study First Submitted QC: 2018-03-06
• Study First Posted: 2018-03-07
• Primary Completion: 2019-12-30
• Study Completion: 2020-01-30
• Status Verified: 2020-04
• Last Update Submitted: 2020-04-14
• Last Update Posted: 2020-04-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. age between 18 and 80 years,
2. chronic cough lasting more than six months
3. earlier thorough diagnosing of cough reason
4. unsuccessful cough management despite at least 3 months of earlier treatment
5. no symptoms of any airway infection during last 4 weeks.

Exclusion Criteria

1. lack of opportunity to participate in speech therapy sessions
2. cough lasting less than 6 months
3. active cigarette smoking
4. taking ACE inhibitors
5. symptoms of airway infection (other than cough).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Cough severity	3 months	measured by Visual Analogue Scale (VAS), range 0-100 mm, the more severe cough , the higher value in VAS score

Secondary Outcome Measures

Name	Time	Method
Sensitivity of cough reflex	3 months	measured by cough challenge test with capsaicin
Cough related quality of life	3 months	measured by Leicester Cough Questionnaire (LCQ)- health related Quality of Life Questionnaire dedicaated for patients, who cough; rangeof total LCQ is 3 to 21 points; higher values represent less intense cough

Trial Locations

Locations (1)

Department of Internal Medicine, Pneumonology and Allergology, Medical University of Warsaw; 🇵🇱 Warsaw, Poland