Morphofunctional Imaging and Developmental Dyslexia

University Hospital, Tours1 site in 1 country32 target enrollmentFebruary 2007

ConditionsDevelopmental Dyslexia

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Developmental Dyslexia
Sponsor: University Hospital, Tours
Enrollment: 32
Locations: 1
Primary Endpoint: Cortical thickness
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Developmental dyslexia is a frequent learning disability. The aim of this study is to analyze cortical thickness and phonological treatment in right handed adults with developmental dyslexia. They are compared to control adults paired with age and laterality. To study phonological treatment, the researchers used functional magnetic resonance imaging (fMRI) with a rime judgement task and silent word generation.

Registry

clinicaltrials.gov

Start Date

February 2007

End Date

February 2008

Last Updated

9 years ago

Study Type

Observational

Sex

Male

Investigators

Sponsor

University Hospital, Tours

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Developmental dyslexia according to Critchley.
•Normal performance intelligence quotient (PIQ)
•Age: 18-35 years
•Sex: Male
•Right handed
•No hearing deficit.

Exclusion Criteria

•No head injury
•No attention deficit hyperactivity disorder (ADHD)

Outcomes

Primary Outcomes

Cortical thickness

Time Frame: 2 years

The average cortical thickness maps of healthy subjects and dyslexic will be compared hemisphere by hemisphere. This will identify whether there are cortical areas including cortical thickness differed significantly between normal and dyslexic.ts of different ages