Prevention of Hand Eczema Among Workers in the Fishing Industry in Greenland

Not Applicable

Recruiting

• Conditions: Hand Eczema

• Registration Number: NCT06997393
• Lead Sponsor: Bispebjerg Hospital

Brief Summary

This study aims to investigate the effect of a prevention programme on hand eczema among workers in the Greenlandic fishing industry. This is a non-randomised clinical trial including employees at four of Royal Greenland's fish processing facilities in Greenland.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2025-05-14
• Study First Submitted QC: 2025-05-21
• Study First Posted: 2025-05-30
• Study Start: 2025-06-10
• Status Verified: 2025-07
• Last Update Submitted: 2025-07-21
• Last Update Posted: 2025-07-24
• Primary Completion: 2025-10
• Study Completion: 2025-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Employee in Royal Greenland, a state-owned company and one of the largest seafood enterprises in the world
• Written informed consent

Exclusion Criteria

• Age below 18 years
• Inability to understand the Greenlandic, Danish or English language
• Pregnancy
• Other chronic skin diseases on the hands
• Receiving immunomodulatory therapies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Change from baseline in knowledge of hand eczema at 3 months	From enrollment to the end of intervention at 12 weeks	Knowledge of hand eczema measured by a self-reported questionnaire
Change from baseline in clinical severity of hand eczema at 3 months	From enrollment to the end of intervention at 12 weeks	Clinical severity of hand eczema measured by Hand Eczema Severity Index (HECSI). The HECSI score ranges from 0 to 360, with higher scores reflecting greater disease severity.

Secondary Outcome Measures

Name	Time	Method
Change from baseline in patient-reported quality of life at 3 months	From enrollment to the end of intervention at 12 weeks	Patient-reported quality of life measured by Hand Eczema Impact Scale (HEIS). The HEIS is a validated 9-item questionnaire that measure the impact of hand eczema on patients' quality of life, based on recall over the past week. Domains include proximal daily activity limitations, embarrassment with the appearance of the hands, frustration with chronic hand eczema, sleep, work, and physical functioning. Each item is scored on a 5-point scale ranging from 0 (not at all) to 4 (extremely). The HEIS score is the average of the 9 items.
Change from baseline in Patient Global Assessment of Disease Severity (PaGA) at 3 months	From enrollment to the end of intervention at 12 weeks	The PaGA rates the severity of the patient's global disease assessed by the patient and is based on a 5-point scale ranging from 0 (clear) to 4 (severe).
Change from baseline in the number of self-reported days with absence from work due to hand eczema at 3 months	From enrollment to the end of intervention at 12 weeks	The number of self-reported days with absence from work due to hand eczema measured by a questionnaire-based interview.
Change from baseline in the number of participants being forced to change their job due to hand eczema at 3 months	From enrollment to the end of intervention at 12 weeks	The number of participants being forced to change their job due to hand eczema measured by a questionnaire-based interview.
Change from baseline in the availability of protective equipment at 3 months	From enrollment to the end of intervention at 12 weeks	The availability of protective equipment (protective gloves, cotton undergloves, moisturisers, and disinfectants) at the workplace measured by a questionnaire-based interview.

Trial Locations

Locations (1)

Royal Greenland; 🇬🇱 Sisimiut, Greenland