ISRCTN43546373
Completed
Not Applicable
Premedication for intubation in neonates: a randomised controlled trial
McMaster University (Canada)0 sites34 target enrollmentOctober 19, 2004
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- McMaster University (Canada)
- Enrollment
- 34
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Newborn infants of all gestations admitted to one Neonatal Intensive Care Unit.
- •Infants of all gestations, admitted to McMaster University Medical Center level III NICU and considered likely to need an elective oral or nasotracheal intubation during their hospital stay, were candidates for inclusion in this study. Families were approached for consent as soon as possible after birth when an elective intubation during their hospital stay seemed likely: if their infant(s) was less than 30 weeks gestation, already ventilated (as endotracheal tubes are frequently changed after 10 days if clinical deterioration from a respiratory standpoint), was on NCPAP for respiratory distress or was needing an elective surgery. Others were approached when an elective intubation was needed. At the time of this study, our unit was a 33\-bed level 3 NICU, caring for both inborn and outborn patients, and the referral center for 25000 annual deliveries, with 900\-1000 admissions per year.
Exclusion Criteria
- •1\. Absence of an intravenous access
- •2\. Upper airway anomaly potentially leading to a difficult intubation
- •3\. Cyanotic heart disease
- •4\. Upper gastrointestinal obstruction (which would require a rapid sequence intubation)
- •5\. Concurrent opioid administration.
Outcomes
Primary Outcomes
Not specified
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