2024-519263-18-00招募中4 期
Prevention of Group G/C Streptococcus Infections during Labour and postpartum - a randomized controlled multicenter trial (POGSI)
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 696
- 试验地点
- 3
- 主要终点
- A postpartum infection of the mother requiring antibiotic treatment up to 3 months after delivery
研究概览
简要总结
To evaluate the efficacy of intrapartum antibiotic profylaxis for the prevention of Group G/C infections of the mother and the newborn
入排标准
- 年龄范围
- 18 years 至 64 years（18-64 Years）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •All pregnant women who are shown by late pregnancy culture (taken at 35+0-38+0 gestational weeks) to carry group G or C Streptococcus in their vaginal-rectal flora are asked to participate
排除标准
- •Exclusion criteria are as follows: The expectant mother carries both Group B Streptococcus (GBS) and group G/C Strptococcus; the expectant mother has had a urinary infection caused by Group B streptococcus at any time during her pregnancy or a previous child with GBS infection, as these women will routinely recieve antibiotic profylaxis;
结局指标
主要结局
A postpartum infection of the mother requiring antibiotic treatment up to 3 months after delivery
A postpartum infection of the mother requiring antibiotic treatment up to 3 months after delivery
次要结局
- Positive blood culture of the mother, mode of delivery, need for blood culture from the newborn, antibiotic treatment of the newborn, transfer to NICU, days in the hospital for the mother and the newborn (lenght of stay after birth/delivery)
研究者
Liisa Laatio
Scientific
University Of Oulu
研究点 (3)
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