High Interval Versus Moderate Intensity Continuous Training on Soluble st2 Biomarkers in Chronic Heart Failure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- soluble ST2 biomarker level
研究概览
简要总结
This study was designed to compare between the effect of high intensity interval training (HIIT) and moderate intensity continuous training (MICT) on soluble ST2 biomarkers among chronic heart failure patients, also measure the improvement in the quality of life with different modes of exercise and with of it is more benifitial for the heart failure patient
详细描述
The data concerned with the study including soluble ST2 biomarker levels, ejection fraction and MLHFQ was measured before and after twelve weeks of treatment.In this study a total sixty male patients with chronic heart failure NYHA class (I &II) were selected from the outpatient clinic, El-Demerdash hospital, Ain-shams University. Their age ranged from 50-60 years. Patients were randomly assigned into two groups, group A receiving HIIT along with prescribed medical treatment and group B receiving MCT along with prescribed medical treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 60 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •The patients selection was according to the following criteria:
- •Patients diagnosed with chronic heart failure (New York heart association class I& II) with systolic left ventricular dysfunction.
- •Their left ventricular ejection fraction (LVEF) <40%.
- •Medical treatment was optimized at least three months prior to study entry.
- •All patients didn't participate in any rehabilitation programs prior to the study.
排除标准
- •Patients who had met one of the following criteria were excluded from the study:
- •Signs of acute heart failure, unstable angina or severe arrhythmia three months prior to enrolment in the study.
- •Pacemakers.
- •Chronic obstructive pulmonary disease.
- •Other disorders counteracting exercise testing conditions that limit lower limb mobility (for example, burns, fractures)
- •Pre-existing neuromuscular diseases (for example Myasthenia Gravis).
结局指标
主要结局
soluble ST2 biomarker level
时间窗: before the start of the trail and at the end of the trail 3 months
sample was taken at the cubited vein at the beginning of the program and also at its end
次要结局
- ejection fraction(before the start of the trail and at the end of the trail 3 months)
- mannisota of daily living questionnaire score(before the start of the trail and at the end of the trail 3 months)
- peak exercise response(before the start of the trail and at the end of the trail 3 months)
研究者
Dina Reda Ali
PhD candidate
Cairo University