Skip to main content
MedPath Trial logoMedPath TrialMedPath Trial Home
Clinical Trials/NCT06402032
NCT06402032CompletedNot Applicable

Clinical and Histological Evaluation of Hesperidin Versus Mineral Trioxide Aggregate (MTA) as a Direct Pulp Capping Material: A Randomized Controlled Trial

Cairo University1 site in 1 country32 target enrollmentStarted: September 1, 2022Last updated:
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
32
Locations
1
Primary Endpoint
Success Rate (Clinical evaluation)
Study OverviewStudy DesignEligibility CriteriaArms & InterventionsOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Direct pulp capping technique is one of the oldest known treatments for exposed pulp tissue, and there is a continuous requirement for the most efficient materials to be used in this approach. Successful pulp capping is the usual way to preserve the vitality of tooth and avoid root canal treatment or surgical tooth extraction.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to 35 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Good oral hygiene,
  • •Sound wisdom teeth with closed apices with normal pulp vitality response
  • •No periodontal disease or periapical lesions on periapical radiograph
  • •Cooperative patients approving to participate in the study

Exclusion Criteria

  • •Medically compromised participants
  • •Evidence of parafunctional habits
  • •Heavy smokers
  • •Teeth with signs and symptoms of irreversible pulpitis or pulp necrosis
  • •Severe periodontal problems or pathological periapical changes
  • •Teeth with open apex or pulp calcification

Arms & Interventions

Mineral trioxide aggregate (MTA)

Active Comparator

Intervention: Mineral Trioxide Aggregate (MTA) (Other)

Hesperidin

Experimental

Intervention: Hesperidin (Other)

Outcomes

Primary Outcomes

Success Rate (Clinical evaluation)

Time Frame: after 12 weeks

Teeth with vital pulp (numerical values with electric pulp tester) and absence of clinical signs/symptoms (Visual Analog Score for pain) as one reported value indicating clinical success rate (%)

Secondary Outcomes

  • Histomorphometric analysis (Histologic evaluation)(after 12 weeks)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Dina Mohamed Kamal Eldin

Lecturer, Faculty of Dentistry

Cairo University

Study Sites (1)

Loading locations...

Similar Trials

Completed
Not Applicable
Histological Evaluation of Hard Tissue Formation After Direct Pulp Capping With RetroMTADental Pulp Exposure
NCT03631511Pomeranian Medical University Szczecin3
Completed
Not Applicable
Clinical Study of the Direct Pulp Capping in Primary TeethPulpotomyPrimary TeethDirect Pulp Capping
NCT05297344The Dental Hospital of Zhejiang University School of Medicine40
Completed
Phase 3
Conservative Pulp Therapy of Primary Molars Using TheraCALReversible Pulpitis
NCT04167943Ain Shams University216
Completed
Not Applicable
3-months Success Rate of Direct Pulp Capping With Biodentine®Dental Pulp Capping
NCT02891876University Hospital, Brest40
Completed
Phase 3
Direct Pulp Capping in Primary MolarsDirect Pulp Capping
NCT05530954Mansoura University52