Estimation of Coronary Artery Hemodynamic Profiles Using Cineangiography Technique

Brief Summary

Detailed Description

\* Methods: Compare TIMI frame count, coronary clearance frame count in baseline/hyperemic coronary angiography with FFR, CFR, IMR and derive correlation, receiver-operating characteristic curve to find new tools estimating coronary hemodynamics by conventional angiography only. A TIMI frame count is measured by counting the angiographic image cine frames during a head of radiocontrast column runs from the entry of left anterior descending artery (LAD) to the distal end. A coronary clearance frame count is measured by counting the angiographic image cine frames during a tail of radiocontrast column runs from the entry of LAD to the distal end. Baseline angiography is performed without any stimulation and hyperemic angiography is performed after intracoronary injection of adenosine 300ug or nicorandiol 2mg. Inclusion criteria * Patient who underwent physiologic study using a pressure wire for intermediate coronary lesion after coronary angiography Exclusion criteria * ST elevation myocardial infarction * Cardiogenic shock * Congestive heart failure with pulmonary edema * LVEF \< 30% * Previous history of coronary revascularization * Chronic total occlusion * 3 vessel disease * Target lesion at distal segments or branches

Primary Outcomes

Secondary Outcomes

• Fractional flow reserve(During the procedure)
• Coronary flow reserve(During the procedure)