Changes in Organ Specific Biomarkers, Virus Expression and Prognosis of Covid-19
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Number of participants with ICU admission or death
研究概览
简要总结
Covid-19 is associated with a wide range of symptoms and clinical trajectories, and early identification of patients at risk for developing severe disease is desirable. Several risk markers and comorbidity profiles have been proposed but their relative importance in unselected patients admitted to hospital with Covid-19 remains unclear. This study aims to assess the prognostic value organ specific biomarkers, viral dynamics and immune response markers in patients infected with SARS-CoV2.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All patients >18 years of age with a positive test for SARS-CoV2 are eligble for inclusion.
- •Healty age-matched volunteers will be included as a control group
排除标准
- 未提供
结局指标
主要结局
Number of participants with ICU admission or death
时间窗: From hospital admission (baseline) until the date of either admission to the ICU or death during the index hospitalization (up to 52 weeks)
Combined outcome measure of either ICU admission or death
次要结局
- Number of participants with ICU admission(From hospital admission (baseline) until the date of admission to the ICU during the index hospitalization (up to 52 weeks))
- Total duration of hospital stay(From hospital admission (baseline) until hospital discharge or death during the index hospitalization (up to 52 weeks))
- Total duration of ICU stay(From admission to the ICU until transfer to another ward, discharge from the hospital or death during the index hospitalization (up to 52 weeks))
- Number of participants with death from all causes(From hospital admission (baseline) unitl the date of death during the index hospitalization (up to 52 weeks))
研究者
Torbjorn Omland
Professor
University Hospital, Akershus