Changes in Organ Specific Biomarkers, Virus Expression and Prognosis of Covid-19
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- COVID
- Sponsor
- University Hospital, Akershus
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Number of participants with ICU admission or death
- Last Updated
- 5 years ago
Overview
Brief Summary
Covid-19 is associated with a wide range of symptoms and clinical trajectories, and early identification of patients at risk for developing severe disease is desirable. Several risk markers and comorbidity profiles have been proposed but their relative importance in unselected patients admitted to hospital with Covid-19 remains unclear. This study aims to assess the prognostic value organ specific biomarkers, viral dynamics and immune response markers in patients infected with SARS-CoV2.
Investigators
Torbjorn Omland
Professor
University Hospital, Akershus
Eligibility Criteria
Inclusion Criteria
- •All patients \>18 years of age with a positive test for SARS-CoV2 are eligble for inclusion.
- •Healty age-matched volunteers will be included as a control group
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Number of participants with ICU admission or death
Time Frame: From hospital admission (baseline) until the date of either admission to the ICU or death during the index hospitalization (up to 52 weeks)
Combined outcome measure of either ICU admission or death
Secondary Outcomes
- Number of participants with ICU admission(From hospital admission (baseline) until the date of admission to the ICU during the index hospitalization (up to 52 weeks))
- Total duration of hospital stay(From hospital admission (baseline) until hospital discharge or death during the index hospitalization (up to 52 weeks))
- Total duration of ICU stay(From admission to the ICU until transfer to another ward, discharge from the hospital or death during the index hospitalization (up to 52 weeks))
- Number of participants with death from all causes(From hospital admission (baseline) unitl the date of death during the index hospitalization (up to 52 weeks))