KCT0008979尚未招募Unknown
A Comparative Study on the Effectiveness and Safety of Thread Embedding Acupuncture(TEA) and Acupuncture in Patients with Knee Osteoarthritis : A Pilot, Assessor-blinded, Randomized, Controlled Trial
Daejeon Korean Medicine Hospital of Daejeon University0 个研究点目标入组 60 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 40(Year) 至 85(Year)（—）
- 性别
- All
入选标准
- •?Those who meet the clinical criteria for primary knee osteoarthritis according to the American College of Rheumatology criteria 3 months prior to screening
- •a. Currently experiencing pain in one or both knees
- •b. and at least three of the following
- •age >50 years, stiffness <30 min, crepitus, bony tenderness, bony enlargement , no palpable warmth
- •?Knee pain during daily activities VAS=40mm
- •?Kellgren-Lawrence Grading Scale Grade 2 or higher according to knee X-ray examination
- •?After receiving a sufficient explanation of the research purpose and implementation process, voluntarily decide to participate and agree in writing.
- •?Anyone who can complete the case report form for the participant on their own or with the assistance
- •?Age 40 to 85 years old (if 75 years old or older, participant judged to have the capacity to consent through consent competency evaluation form)
排除标准
- •?History of severe trauma to the knee, such as cartilage damage and cruciate ligament rupture.
- •?History of infectious or inflammatory diseases of the knee, such as bacterial arthritis, tuberculous arthritis, or gout
- •?Congenital deformity of the knee joint
- •?Those who have a history of invasive procedures such as knee replacement surgery or proximal tibial osteotomy (excluding knee arthroscopy) or who have a plan within the study period
- •?Received intra-articular injection treatment of steroids, hyaluronic acid, prolotherapy, PRP (Platelet-Rich Plasma), etc. within the past 6 months.
- •?Received TEA or other invasive treatment for the knee joint within the past 6 months, or received acupuncture or other oriental medicine treatment within the past 2 weeks.
- •?Screening clinical examination ESR>40mm/h, RA Factor>20U/mL
- •?Aspartate aminotransferase (8-40IU/L) and alanine aminotransferase (5-43IU/L) are more than three times higher than normal levels.
- •?Blood urea nitrogen (BUN, 5-23mg/dL) and creatinine (0.6-1.3mg/dL) are more than three times higher than normal levels.
- •?musculoskeletal problem that causes more pain in another part of the body than in the knee
- •?Taking narcotic analgesics, anticonvulsants, or corticosteroids for pain control within the past week
- •?Acupuncture hypersensitivity, metal allergy, severe atopy, keloid skin, other skin sensitivities, etc.
- •?Factors that can affect hemostasis, such as taking anticoagulants and antiplatelet drugs, and bleeding disorders
- •?Pregnant, lactating, or planning to become pregnant within the clinical trial period
- •?Uncontrolled diabetes, serious cardiovascular disease (myocardial infarction, congestive heart failure, etc.), etc.
- •?Are receiving or need active treatment due to significant neuropsychiatric medical history, history of alcohol or drug abuse, or serious underlying disease.
- •?Less than 1 month has passed since the end of participation in another interventional clinical study (including human trials), or the person was selected for this clinical study and plans to participate in other interventional clinical studies (including human trials) while participating.
- •?Clinical research staff determines it is inappropriate
研究者
相似试验
已完成
不适用
A comparative study on the effectiveness and safety of Azadirachta indica leaf extract versus chlorhexidine mouth rinses on postoperative complications following mandibular third molar surgeries: a randomized, double-blinded controlled study.Oral HealthPACTR202301888753718Dr. Patience Ewere Ofiri42
尚未招募
3 期
Crisaborole vesus tacrolimus ointment in the treatment of atopic dermatitisCTRI/2024/05/067660Dr Disha Chakraborty
尚未招募
Unknown
A comparison of efficacy and safety of Antihypertensive drugs used in combination and adherence to medication in patients of HypertensioCTRI/2023/09/057435Dr. Madhumita Dixit
招募中
2 期
Evaluation of the efficacy of Olanzapine and Aripiprazole in patients with psychotic disordersIRCT20200430047250N1Kermanshah University of Medical Sciences94
招募中
不适用
The comparative study about the efficacy and safety of alternative DPP-4 (dipeptidyl peptidase-4) inhibitor sitagliptin and the rapid-acting insulin secretagogue (glinide) in patients with type 2 diabetesJPRN-UMIN000003479Mie Chuo Medical Center (Mie Prefecture)80