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Clinical Trials/NCT00995319
NCT00995319
Completed
Not Applicable

Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area

Norwegian University of Science and Technology1 site in 1 country58 target enrollmentJanuary 2008

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Head and Neck Cancer
Sponsor
Norwegian University of Science and Technology
Enrollment
58
Locations
1
Primary Endpoint
salivary flow
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The purpose of this clinical investigation is to evaluate acute and longlasting side effects in patients undergoing radiotherapy for cancer treatment in the head and neck area.

Detailed Description

The "Dental Team" at the Department for Oral and Maxillofacial Surgery in Trondheim takes care of patients before, during and also after radiotherapy in the head and neck area. In spite of the use of advanced radiation protocols and prevention measures such as fluoridation splints the team observes significant side effects, both under radiation and also on the long term after concluding treatment. Common problems are for example dermal and mucosal damages, reduced salivation, dysphagia and lesions of the teeth. Aim of the study is the investigation and documentation of side effects and complications in relation to the oral cavity. During the acute and postradiation phase a continuous follow-up over a longer lasting period is proceeded with registration of all relevant parameters. This includes among others dental status and evaluation of quality of life.

Registry
clinicaltrials.gov
Start Date
January 2008
End Date
July 2014
Last Updated
9 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • radiation concerning the oral cavity
  • follow-up at the Dental Team

Exclusion Criteria

  • refused approval
  • survival prognosis under one year

Outcomes

Primary Outcomes

salivary flow

Time Frame: 12 months

Study Sites (1)

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