Managing the Nutritional Needs of Older Filipino with Due Attention to Protein Nutrition and Functional Health Study
- Conditions
- Sarcopenia
- Interventions
- Dietary Supplement: Nutrition supplementationOther: Exercise
- Registration Number
- NCT05953116
- Lead Sponsor
- Food and Nutrition Research Institute, Philippines
- Brief Summary
The study aims to determine the effect of protein nutrition and exercise on the body composition and functional capacity of Filipino older adults.
- Detailed Description
The objective of the study is to determine the effects of nutrition supplementation and exercise intervention on the main indicators of sarcopenia in older adults such as body composition (fat mass and lean mass), muscle strength (leg and handgrip), and physical performance.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 68
- Pre-sarcopenia/pre-frail
- Aged 60 years old and above, male or female
- Free-living in the community, ambulatory
- Able to respond to food recall/interview as self-declared
- Normal cardiac function as measured by resting ECG
- Bed ridden, unable to perform exercise independently
- Presence of serious medical condition (i.e. cancer, existing fracture)
- Presence of unmanaged hypertension and/or type 2 diabetes or upon assessment of physician
- Renal Problem
- Under controlled or medically-supervised diet not flexible to include the intervention agent
- Allergic to any ingredients in the nutrition supplementation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo Group Exercise An isocaloric product (made with maltodextrin) in powdered form with flavoring. Product will be added to 180-200 mL of warm water prior to consumption. Intervention Group Exercise A protein product (combination of whey protein and plant-derived protein) in powdered form with flavoring. Product will be added to 180-200 mL of warm water prior to consumption. Intervention Group Nutrition supplementation A protein product (combination of whey protein and plant-derived protein) in powdered form with flavoring. Product will be added to 180-200 mL of warm water prior to consumption. Placebo Group Nutrition supplementation An isocaloric product (made with maltodextrin) in powdered form with flavoring. Product will be added to 180-200 mL of warm water prior to consumption.
- Primary Outcome Measures
Name Time Method Change in muscle strength, as measured by grip strength and leg strength (Jamar, MicroFET) Baseline, Midline (6 weeks), Endline (12 weeks) Handgrip strength is measured using a hydraulic hand dynamometer through maximum exertion of grip force (in kilograms).
Leg strength is measured using a hand-held dynamometer. Participant will use strongest leg force to push against the resistance brought upon by the researcher while holding the measuring device.Change in physical performance, as measured by timed up-and-go test Baseline, Midline (6 weeks), Endline (12 weeks) Faster time duration to complete the test indicate lesser risk for falls
Change in physical performance, as measured by short physical performance battery Baseline, Midline (6 weeks), Endline (12 weeks) Score ranges from 0 to 12 with a higher score indicating better functionality
Change in physical performance, as measured by 10-meter walk test Baseline, Midline (6 weeks), Endline (12 weeks) Faster walking speed (in meters per second) indicate better functionality
Change in muscle mass, as measured by dual-energy x-ray absorptiometry (DXA) Baseline, Midline (6 weeks), Endline (12 weeks) Measurement of appendicular skeletal muscle mass index (ASMI) by dividing total muscle mass (kg) of appendages with height in meters squared
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Science and Technology-Food and Nutrition Research Institute
🇵ðŸ‡Taguig, Metro Manila, Philippines