Norepinephrine Administration Through a Midline Catheter in an Intermediate Care Unit

Completed

• Conditions: Hypotension and Shock; Septic Shock; Norepinephrine Adverse Reaction

• Registration Number: NCT06121115
• Lead Sponsor: Region Skane

Brief Summary

This is a single-center study retrospectively evaluating a local clinical routine to administer norepinephrine in midline catheters, with regard to complications and patient outcomes

Detailed Description

Se attached study protocol

Study Timeline

• Study Start: 2023-10-03
• Study First Submitted: 2023-10-03
• Study First Submitted QC: 2023-11-05
• Study First Posted: 2023-11-07
• Status Verified: 2024-03
• Primary Completion: 2024-03-01
• Study Completion: 2024-03-01
• Last Update Submitted: 2024-03-11
• Last Update Posted: 2024-03-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 473

Inclusion Criteria

• Administration of norepinephrine in a midline catheter in an intermediary care unit
• In Skåne university hospital
• From 2019 to 2023-03-31

Exclusion Criteria

• Patients who have actively disabled review of their electronic medical record

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of patients with a major complication of norepinephrine administration in midline	day 30	extravasation of norepinephrine, midline-associated bloodstream infection, thrombosis

Secondary Outcome Measures

Name	Time	Method
Proportion of patients receiving a CVC after midline	day 30	Has the patient received central line after midline placement
Proportion of patients with a minor complication of norepinephrine administration in midline	day 30	infiltration, occlusion of midline, dislodgement, leakage, other
Proportion of patients with different intermediary care unit outcomes	day 30	Where did the patient go after intermediary care? discharged / escalated to the ICU / deceased

Trial Locations

Locations (1)

Skåne University Hospital; 🇸🇪 Malmö, Sweden