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Safety of a Quadrivalent Influenza Vaccine (VaxigripTetra™) in Subjects Aged 6 Months and Older in Vietnam

Phase 3
Completed
Conditions
Influenza
Interventions
Biological: Quadrivalent Influenza Vaccine
Registration Number
NCT03765437
Lead Sponsor
Sanofi Pasteur, a Sanofi Company
Brief Summary

The primary objective of this study is to describe the safety of the Quadrivalent Influenza Vaccine (QIV). Safety is assessed throughout the study period, and includes solicited injection site and systemic reactions (Day 0 to Day 7 post-vaccination); unsolicited adverse events up to Day 28, and serious adverse events occurring throughout the study.

Detailed Description

Study duration for previously unvaccinated participants aged 6 months to 8 years is approximately 56 days. Study duration for previously vaccinated participants aged 6 months to 8 years and any participant aged 9 years and older is approximately 28 days.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
230
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Quadrivalent Influenza VaccineQuadrivalent Influenza VaccineQuadrivalent Influenza Vaccine (split-virion, inactivated) Northern hemisphere seasonal formulation 2018-2019
Primary Outcome Measures
NameTimeMethod
Number of participants reporting solicited injection site reactions or systemic reactionsWithin 7 days after vaccination

Injection site reactions: tenderness/pain, erythema, swelling, induration, and haemorrhage.

Systemic reactions: participants ≤ 23 months: fever, vomiting, crying abnormal, drowsiness, appetite lost, and irritability; participants 2 years and older: fever, headache, malaise, myalgia, and shivering.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Investigational Site Number 7040001

🇻🇳

Viet Tri, Vietnam

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