6-MP studie.
Recruiting
- Conditions
- Acute Myeloid leukemiaAcute myeloide leukemie
- Registration Number
- NL-OMON28582
- Lead Sponsor
- Prof.dr. E. VellengaDept. of HematologieUniversity Medical Center GroningenP.O. Box 30.0019700 RB GroningenThe Netherlands
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 18
Inclusion Criteria
1. Age >18 years;
2. Diagnosed with (relapsing) AML and not eligible for intensive chemotherapy.
Exclusion Criteria
Ineligible or not willing to perform the proposed tests.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Expression of multidrug-resistance genes, nuclear receptors and in vitro susceptibity for 6-MP;<br /><br>2. Changes in the lymphoid compartment during treatment with 6-MP;<br /><br>3. HLA-type;<br /><br>4. Clinical response on treatment with 6-MP.<br>
- Secondary Outcome Measures
Name Time Method