The influence of prostaglandins and prostaglandin receptors on the cervix opening at the end of pregnancy and at the beginning of labor
Recruiting
- Conditions
- Physiology birth process
- Registration Number
- DRKS00017221
- Lead Sponsor
- niversitätsklinikum Frankfurt a. Main
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 160
Inclusion Criteria
Pregnant, nullipara, no pathologies of cervix uteri, ages 18-42 years
Exclusion Criteria
Cervical insufficiency in this pregnancy, multiple pregnancy, planned primary cesarean section, multiparous, premature rupture of membranes before 37 + 0 weeks of pregnancy, known cervical dysplasia, known cervical carcinoma, earlier conization of the cervix
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cervical ripening according to Bishop score<br>mode of delivery<br>Time to complete opening of the cervix<br>Time to delivery of the child from regular labor<br>Expression of prostaglandin receptors at the uterine cervix and at the lower uterine segment at different times shortly before estimated day of delivery and delivery
- Secondary Outcome Measures
Name Time Method Marker of the glucose metabolism<br>Prostaglandin metabolite levels in the mother's blood and umbilical cord blood