Carperitide in Acute Respiratory Distress Syndrome (ARDS)

Phase 2

Completed

• Conditions: Respiratory Distress Syndrome

• Registration Number: NCT00030121
• Lead Sponsor: Suntory Pharmaceutical

Brief Summary

The purpose of this study is to determine whether Carperitide is safe and effective in the management of Acute Respiratory Distress Syndrome (ARDS).

Detailed Description

Acute respiratory distress syndrome (ARDS is a severe form of acute lung injury. ARDS is characterized by an increase in pulmonary vascular permeability resulting from a non-cardiogenic cause, leading to an increased vascular water volume, pulmonary inflammation, and severe hypoxemia. Conventional therapy for ARDS is primarily respiratory management by mechanical ventilation using positive end-expiratory pressure (PEEP). Mechanical ventilation is the major management concern in patients with ARDS, due to its higher risk of infections and morbidity. Treatment with Carperitide may reduce time on the ventilator by reducing pulmonary edema and by improving gas exchange. The results of Carperitide studies in animals and humans support the idea that the hormone will be effective in managing the acute pulmonary complications and hypoxemia seen in ARDS.

Study Timeline

• Study Start: 1999-12
• Study First Submitted: 2002-01-31
• Study First Submitted QC: 2002-01-31
• Study First Posted: 2002-02-01
• Status Verified: 2008-02
• Last Update Submitted: 2008-02-19
• Last Update Posted: 2008-02-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL