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To Compare the efficacy Varma manipulation with Sukku Kashayam III (Internal) and Vasavu Ennai VI (External) in the Treatment of Azhal keel vayu

Phase 2
Completed
Conditions
Health Condition 1: M170- Bilateral primary osteoarthritis of knee
Registration Number
CTRI/2021/02/031317
Lead Sponsor
Government Siddha Medical College and Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

�Patient having the symptoms of Knee Joint Pain, Stiffness, Tenderness, Crepitation and Restricted movement of Knee joint.

�Patients who are willing to give blood samples for laboratory investigation.

�Patients who are willing to take X-ray before and after treatment.

�Patients who are willing to participate in this study with the knowledge of potential risks and who are willing to sign the informed consent form.

Exclusion Criteria

1 History of Trauma and fracture, Ligament injury

2 Other types of Arthritis (Rheumatoid Arthritis, Psoriatic Arthritis, Septic Arthritis, Reactive Arthritis etc.,)

3 Diabetes Mellitus and Hypertension

4 Pregnancy women and lactating mothers.

5 Benign and malignant Neoplasm

6 Patient with any other Autoimmune Diseases.

7 Patient who are having the skin disease

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Assessment of change from baseline in WOMAC score at day of 48 between Group I & Group II for Varma manipulation and Internal& External medicine <br/ ><br> <br/ ><br>Comparison of radiological changes from baseline in Kellgren-Lawrence Grading Scale at day of 48 between Group I & Group II <br/ ><br> <br/ ><br>Timepoint: 48 days <br/ ><br> <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
Assessment of quality of life by EQ-5D. <br/ ><br>Assessment of safety parameters. <br/ ><br>Timepoint: 48 days
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