Pilot Investigation on the Effects of Sub Acute (12 Week) Home Base Whole-body Vibration Training in Osteoarthritis.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Change in Pain Pressure Threshold assessed using the Jtech Medical Echo Algometer
研究概览
简要总结
The purpose of this proposal is to understand how the Vibrant Health Ultimate whole-body vibration (WBV) machine affects pain and inflammation in older adults. The investigators' hypothesize that sub-acute (12 weeks) WBV will lead to improvement in the level of knee pain and improve vascular function via a decrease in systemic inflammation.
详细描述
Knee osteoarthritis (KO) is a leading cause of disability and medical cost. Whole body vibration (WBV) has emerged as an exercise alternative that may be more tolerable than traditional forms of exercise, such as treadmill walking/running or cycling. Similar to traditional exercise, research supports that WBV can be very beneficial for your health. In fact, a single bout of WBV increases circulating concentrations of inflammatory markers. WBV is safe and effective, WBV training has been conducted in obesity, elderly, patients with diabetes, patients with lung disease, as well as patients with knee osteoarthritis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Symptomatic Osteoarthritic knee pain for at least 6 months.
- •Mean and women
- •Ages 40-75 years old
排除标准
- •<40 years old or >75 years old
- •History of balance issues
- •History of falls
- •Pregnancy
- •The use of whole-body vibration in the past 6 months
- •Previous knee surgery within last 3 years
- •Unable to stand for at least 20 minutes (for whole body vibration training)
研究组 & 干预措施
Whole Body Training (12 week)
干预措施: Sub Acute Whole Body Vibration Training (Device)
结局指标
主要结局
Change in Pain Pressure Threshold assessed using the Jtech Medical Echo Algometer
时间窗: pre-treatment baseline and following 12 weeks sub-acute whole-body vibration
change from baseline pain pressure threshold at 12 weeks. Pain Pressure Threshold (PPT) will be assessed using the Jtech Medical Echo Algometer. PPT is used to measure deep muscular tissue sensitivity. The test determines the amount of pressure over a given area in which a steadily increasing non-painful pressure stimulus turns into an uncomfortable or painful pressure sensation. The subject will lie supine. An investigator will assess PPT at the following sites: a) 2 cm below the medial edge of the patella and b) 2 cm below the lateral edge of the patella. Using the 1 cm2 probe, the investigator will place it perpendicular to each site and apply pressure at a rate of 0.5 kg/cm2/s. Each trial will stop when the subject reports pain. The investigator will take 3 trials at each site; the average of the 3 trials, recorded in kg/cm2, will be used for statistical analysis.
次要结局
- Change in Pulse Wave Velocity (PWV)(pre-treatment baseline and following 12 weeks sub-acute whole-body vibration)
- Change in IL-6(pre-treatment baseline and following 12 weeks sub-acute whole-body vibration)