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Clinical Trials/ISRCTN26287422
ISRCTN26287422
Completed
未知

Probiotics in the prevention of atopy in infants and children (PROBAT)

niversity of Wales, Swansea (UK)0 sites454 target enrollmentJune 15, 2005
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ConditionsAtopy in infants and childrenSigns and SymptomsAtopy

Overview

Phase
未知
Intervention
Not specified
Conditions
Atopy in infants and children
Sponsor
niversity of Wales, Swansea (UK)
Enrollment
454
Status
Completed
Last Updated
3 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

Abstract results in http://dx.doi.org/10.1136/archdischild-2012-301885.5 results in: Allen SJ, Jordan S, Storey M, Thornton C, Gravenor M, et al.. () Probiotics and atopic eczema: A double-blind randomised controlled trial. Arch Dis Child 97 S1 A2 P05. 2010 Results article in http://www.ncbi.nlm.nih.gov/pubmed/20089774 results 2014 Results article in http://www.ncbi.nlm.nih.gov/pubmed/24947281 results 2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/29769554 5-year extension results (added 24/10/2019) 2013 Results article in https://pubmed.ncbi.nlm.nih.gov/23874465/ (added 28/06/2021)

Registry
who.int
Start Date
June 15, 2005
End Date
July 31, 2021
Last Updated
3 years ago
Study Type
Interventional
Sex
Female

Investigators

Sponsor
niversity of Wales, Swansea (UK)

Eligibility Criteria

Inclusion Criteria

  • •600 women and their newborn infants recruited from the antenatal department of a maternity unit of a district general hospital, with informed written consent. Infants have a first degree relative with an atopic disorder.

Exclusion Criteria

  • •1\. Mother aged less than 16 years
  • •2\. Multiple pregnancy
  • •3\. Gestation at delivery less than 36 weeks
  • •4\. Parents unable or unwilling to give informed consent
  • •5\. Any adverse medical condition affecting the pregnancy or its likely outcome (e.g. known abnormality in foetus)
  • •6\. Member of sibship or household already recruited to the study

Outcomes

Primary Outcomes

Not specified

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