ISRCTN26287422已完成未知
Probiotics in the prevention of atopy in infants and children (PROBAT)
niversity of Wales, Swansea (UK)0 个研究点目标入组 454 人开始时间: 2005年6月15日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 454
研究概览
简要总结
Abstract results in http://dx.doi.org/10.1136/archdischild-2012-301885.5 results in: Allen SJ, Jordan S, Storey M, Thornton C, Gravenor M, et al.. () Probiotics and atopic eczema: A double-blind randomised controlled trial. Arch Dis Child 97 S1 A2 P05. 2010 Results article in http://www.ncbi.nlm.nih.gov/pubmed/20089774 results 2014 Results article in http://www.ncbi.nlm.nih.gov/pubmed/24947281 results 2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/29769554 5-year extension results (added 24/10/2019) 2013 Results article in https://pubmed.ncbi.nlm.nih.gov/23874465/ (added 28/06/2021)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Female
入选标准
- •600 women and their newborn infants recruited from the antenatal department of a maternity unit of a district general hospital, with informed written consent. Infants have a first degree relative with an atopic disorder.
排除标准
- •1. Mother aged less than 16 years
- •2. Multiple pregnancy
- •3. Gestation at delivery less than 36 weeks
- •4. Parents unable or unwilling to give informed consent
- •5. Any adverse medical condition affecting the pregnancy or its likely outcome (e.g. known abnormality in foetus)
- •6. Member of sibship or household already recruited to the study
研究者
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