Amlodipine vs Nitrates Study in Patients With Chronic Stable Angina
Phase 4
Completed
- Conditions
- Myocardial Ischemia
- Registration Number
- NCT00143195
- Lead Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
- Brief Summary
The objective of study is to compare the anti-ischemic efficacy and safety profiles of once daily amlodipine or isosorbide-5-mononitrate in the treatment of stable asymptomatic and symptomatic myocardial ischemia
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- Outpatients > =18 years of age with diagnosed clinically stable angina pectoris
Exclusion Criteria
- Patients with congestive heart failure, clinically significant cardiovascular disease, standing systolic blood pressure of less than 100mmHg, concomitant anti-anginal therapies similar to sublingual NTG
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Evaluate the time to 1mm ST depression
- Secondary Outcome Measures
Name Time Method The number of patients experiencing angina attacks The frequency of hospitalizations due to angina attacks Time to onset of 1mm ST segment depression Total external workload performed Safety
Trial Locations
- Locations (1)
Pfizer Investigational Site
🇬🇷Zakynthos, Greece