Comparative study of topical TCA %50 and cultured autologous fibroblasts in the treatment of the atrophic scars of face.(Pilot Study)

Early Phase 1

• Conditions: atrophic scar.; Scar conditions and fibrosis of skin

• Registration Number: IRCT138902081159N2
• Lead Sponsor: Isfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Age more than 18 years, dissatisfaction of facial appearance, Negative pregnancy test at the screening visit, signing written informed consent, compliance with the study requirements, Healthy, non-scarred skin for biopsy

Exclusion Criteria

Previous treatment with dermal filler or other method, participating in another clinical trial, History of autoimmune disease or organ transplantation, History of cancer, Active systemic infection, need to chronic antibiotic or steroidal therapy, Using systemic agents that increase bleeding or clotting, any disorder that increase bleeding or clotting, Pregnancy or breast feeding, Known allergic reaction to components of study treatment and/or study injection procedure, Excessive exposure to sun or sunburn in the post-auricular area, Patients with psychological disorders

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Scar size. Timepoint: before and after the intervention. Method of measurement: Photography of scar before beginning of the study and millimeter paper.

Secondary Outcome Measures

Name	Time	Method
Cinical improvement of scar. Timepoint: Before the study and 3, 6, and 12 months after the beginning of study. Method of measurement: Photography of scar at each visit.