Impact of Infectious Diseases Consultation on Vaccination Coverage Among People Waiting for a Kidney Transplant at the Clermont-Ferrand Hospital
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- Vaccination coverage
研究概览
简要总结
Solid-organ transplant patients are at increased risk of infectious diseases. Among this population, infectious diseases may be life-threatening or lead to graft rejection. Their prevention is an important challenge. Despite specific national recommendations, vaccination is underutilized. That is why we propose a dedicated infectious diseases consultation during pre-kidney transplantation assessment.
详细描述
The main objective of this study is to impove vaccine coverage before kidney transplantation.
Enrollment was based on the waiting list for a kidney transplant. Patients newly listed are invited to participate by the transplant team (nephrology department) ; for those that are already registered, a notification letter is sent to their home.
All patients included must :
- complete a health questionnaire
- take a blood test at day 0 : viral, bacterial and parasitic serologies, QuantiFERON-TB
- take a chest X-ray and dental panoramic Patients randomized in interventional group will be seen in specific infectious diseases consultation at Clermont Ferrand Hospital. A letter of recommendations is sent to nephrologist for patients randomized in group control.
The primary study endpoint (immunization coverage) is evaluated at 6 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient over 18
- •On the waiting list for kidney transplantation at Clermont-Ferrand
- •Free and informed consent
- •Affiliation to a social security system
排除标准
- •Patient under 18
- •Protected adults (individuals under guardianship by court order
- •Pregnant and nursing women
- •Prior graft (solid organs or hematopoietic stem cells)
- •Absence of consent
结局指标
主要结局
Vaccination coverage
时间窗: Month 6
The percentage of fully immunized patients according to the Recommendations of High Council for public Health
次要结局
- Mortality(Month 6)
- Infectious complications(within the 6 months of the transplantation)