Right Ventricular Function scoring and its Utility among patients with Sepsis and Septic shock
Not Applicable
- Conditions
- Health Condition 1: A419- Sepsis, unspecified organism
- Registration Number
- CTRI/2023/08/056086
- Lead Sponsor
- AIIMS, New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
With a diagnosis of sepsis acute change in total SOFA score >=2 points consequent to the infection according to Sepsis 3 definition and
septic shock- defined as sepsis with persisting hypotension requiring vasopressors to maintain a MAP >= 65 mmHg and having a serum lactate level > 2 mmol/L despite adequate volume resuscitation.
Exclusion Criteria
1 New Onset ACS within 1 Week
2Diagnosed heart failure, severe valvular heart disease such as severe mitral or aortic stenosis or tricuspid stenosis or regurgitation/prosthetic heart valves
3Chronic pulmonary disease requiring long-term oxygen therapy, Known case of moderate to severe Pulmonary hypertension/ corpulmonale
4Pregnancy
5 inadequate echocardiographic window
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine the ability of the 5- parameter Right Ventricular Dysfunction Score (RVD) score in predicting 28- day all-cause mortality among septic patients.Timepoint: Baseline, 48hrs- RVD Score <br/ ><br>28day mortality
- Secondary Outcome Measures
Name Time Method 1To establish relationship between RVD Score and: <br/ ><br>a Mechanical Ventilation duration <br/ ><br>b.Vasopressor free days <br/ ><br>c. Need for Renal Replacement Therapy <br/ ><br>d. ICU length of stay <br/ ><br>2. To compare RVD score & Tricuspid Annular Plane Systolic Excursion/Pulmonary Artery Systolic Pressure ratio in predicting 28-day all-cause mortality among patients with sepsis & septic shock. <br/ ><br>Timepoint: 28 days