Continuous Local Anaesthetic Wound Infiltration in Hepatobiliary Surgery - A Comparison with Placebo

• Conditions: Post-hepatobiliary surgery; Anaesthesiology - Pain management; Surgery - Other surgery; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12610000832077
• Lead Sponsor: Dr Lauren Radford

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-10-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

1. Undergoing elective open hepatobiliary surgical procedure
2. American Society of Anaesthesiologists (ASA) physical status I, II or III
3. Physically and mentally able to use patient-controlled analgesia (PCA) machine

Exclusion Criteria

1. Contraindication or known allergy to local anaesthetic drug
2. Preoperative cognitive dysfunction
3. Preoperative diagnosis of chronic pain or opiate tolerance

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improved visual analogue pain scores when compared with placebo[First 48 hours post-operative (assessed at 1, 2, 6, 12, 18, 24, 30, 36, 42 and 48 hours)]

Secondary Outcome Measures

Name	Time	Method
Reduced opiate consumption as measured by total dose required by patient-controlled analgesia (PCA) machine[First 48 hours post-operative (assessed at 1, 2, 6, 12, 18, 24, 30, 36, 42 and 48 hours)];Reduced opiate side effects (eg. sedation, nausea and vomiting) using our hospital's Acute Pain Service patient-based numerical rating scale[First 48 hours post-operative (assessed at 1, 2, 6, 12, 18, 24, 30, 36, 42 and 48 hours)]