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COVID-19 and SARS-CoV-2 Detection in Saliva

Completed
Conditions
RNA Virus Infections
Interventions
Diagnostic Test: RT-PCR
First Posted Date
2020-08-18
Last Posted Date
2022-03-07
Lead Sponsor
Ambry Genetics
Target Recruit Count
67
Registration Number
NCT04517682
Locations
🇺🇸

Ambry Genetics, Aliso Viejo, California, United States

A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors

Phase 1
Recruiting
Conditions
Solid Tumor
Interventions
Biological: CLDN6 CAR-T
Biological: CLDN6 uRNA-LPX/CLDN6 modRNA-LPX
First Posted Date
2020-08-07
Last Posted Date
2025-05-22
Lead Sponsor
BioNTech Cell & Gene Therapies GmbH
Target Recruit Count
147
Registration Number
NCT04503278
Locations
🇦🇺

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

🇩🇪

Charité - Universitätsmedizin Berlin - Campus Benjamin Franklin, Berlin, Germany

🇩🇪

Universitätsklinikum Erlangen - Hämatologie & Intrinsische Onkologie - Medizinische Klinik 5, Erlangen, Germany

and more 9 locations

Assessment of the TGF-beta Pathway and Micro-RNA in Pediatric Pulmonary Arterial Hypertension

Conditions
Pulmonary Arterial Hypertension
Interventions
Diagnostic Test: Protein Elisa analysis, microRNA analysis, whole exome sequencing
First Posted Date
2020-07-28
Last Posted Date
2021-11-22
Lead Sponsor
Medical College of Wisconsin
Target Recruit Count
40
Registration Number
NCT04489251
Locations
🇺🇸

Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States

Advanced Translational Research on Childhood Leukemia

Recruiting
Conditions
Childhood Leukemia
Interventions
Genetic: RNA-seq
Genetic: whole exon sequencing
Other: Cytogenetics test
First Posted Date
2020-07-20
Last Posted Date
2023-09-25
Lead Sponsor
Chinese University of Hong Kong
Target Recruit Count
150
Registration Number
NCT04478006
Locations
🇨🇳

Hong Kong Children Hospital, Hong Kong, Hksar, China

RNA Precision Oncology in Advanced Pancreatic Cancer

Not Applicable
Terminated
Conditions
Pancreatic Cancer
Interventions
Device: OncoTreat
First Posted Date
2020-07-20
Last Posted Date
2025-04-03
Lead Sponsor
Columbia University
Target Recruit Count
16
Registration Number
NCT04476537
Locations
🇺🇸

Columbia University Irving Medical Center, New York, New York, United States

Comparison of Tocilizumab Plus Dexamethasone vs. Dexamethasone for Patients With Covid-19

Phase 2
Completed
Conditions
RNA Virus Infections
Coronavirus Infection
SARS (Severe Acute Respiratory Syndrome)
Virus Diseases
Coronaviridae Infections
Respiratory Tract Disease
Respiratory Tract Infections
Nidovirales Infections
Interventions
First Posted Date
2020-07-20
Last Posted Date
2024-05-31
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
453
Registration Number
NCT04476979
Locations
🇬🇫

CH Andrée Rosemon, Cayenne, French Guiana

Evaluation of an Alternative Method of Obtaining Viral RNA for the Detection of SARS-CoV-2 Virus Using PCR

Conditions
COVID
Corona Virus Infection
SARS-CoV2
Interventions
Diagnostic Test: Obtainment of nasopharyngeal, oropharyngeal, buccal, nasal and saliva samples
First Posted Date
2020-07-13
Last Posted Date
2020-07-13
Lead Sponsor
Neurognos
Target Recruit Count
150
Registration Number
NCT04468217
Locations
🇨🇱

Laboratorio Neurognos, Santiago, Providencia, Chile

COVID-19 (SARS-CoV-2) in Urine and Semen

Completed
Conditions
Sexual Function and Fertility Disorders
Urine
Urinary Function Disorders
SARS-CoV 2
Semen
Interventions
Diagnostic Test: SARS-CoV 2 RNA PCR Urine
Diagnostic Test: SARS-CoV 2 RNA PCR Semen
Diagnostic Test: Semen Qualitative Analysis
Diagnostic Test: IIEF-5 questionnaire
Diagnostic Test: Male Sexual Health Questionnaire (MSHQ)
Diagnostic Test: IPSS questionnaire
Diagnostic Test: SECRET questionnaire
Diagnostic Test: Interleukin assessment in semen
First Posted Date
2020-06-24
Last Posted Date
2021-10-11
Lead Sponsor
University of Florence
Target Recruit Count
43
Registration Number
NCT04446169
Locations
🇮🇹

AOU Careggi, Florence, Tuscany, Italy

Activation of miRNA and Proteins After Acute Experimental Pain. (miRNA: Micro RNA)

Not Applicable
Completed
Conditions
Isotonic Saline
Hypertonic Saline
Interventions
Other: hypertonic saline
Other: Saline injection
Procedure: Blood sampling
First Posted Date
2020-06-19
Last Posted Date
2023-10-03
Lead Sponsor
Aalborg University
Target Recruit Count
20
Registration Number
NCT04439994
Locations
🇩🇰

AAlborg University, Aalborg, Nordjylland, Denmark

🇩🇰

Aalborg University, Aalborg, Nordjylland, Denmark

Microbial Profiling in Pockets Related to Chronic Periodontitis Patients Using 16s RNA Metagenomics Sequencing

Not Applicable
Completed
Conditions
Periodontal Diseases
Interventions
Genetic: 16s RNA Metagenomics sequencing
First Posted Date
2020-06-11
Last Posted Date
2020-06-11
Lead Sponsor
Ajman University
Target Recruit Count
80
Registration Number
NCT04425343
Locations
🇦🇪

Ajman University of Science and Technology, Ajman, United Arab Emirates

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