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Lot-to-lot Consistency of a Plant-Derived Quadrivalent Virus-Like Particles Influenza Vaccine in Healthy Adults

Phase 3

Completed

Conditions: Virus Diseases
Respiratory Tract Infections
Respiratory Tract Disease
Influenza
RNA Virus Infections

Interventions: Biological: Quadrivalent VLP Influenza Vaccine

First Posted Date: 2017-10-26

Last Posted Date: 2023-08-04

Lead Sponsor: Medicago

Target Recruit Count: 1202

Registration Number: NCT03321968

Locations: 🇨🇦
Site 207, Guelph, Ontario, Canada
🇨🇦
Site 205, Halifax, Nova Scotia, Canada
🇨🇦
Site 208, Burlington, Ontario, Canada

and more 7 locations

Impact of Sofosbuvir and Daclatasvir Concentration on HCV RNA

Completed

Conditions: Hepatitis C

Interventions: Drug: Sofosbuvir/daclatasvir with or without ribavirin

First Posted Date: 2017-10-24

Last Posted Date: 2017-10-24

Lead Sponsor: Hospices Civils de Lyon

Target Recruit Count: 130

Registration Number: NCT03318887

Locations: 🇫🇷
Croix-Rousse Hospital, Hospices Civils de Lyon, Lyon, France

Efficacy, Safety, and Immunogenicity of a Plant-Derived Quadrivalent Virus-Like Particles (VLPs) Influenza Vaccine in Adults

Phase 3

Completed

Conditions: Respiratory Tract Infections
Virus Diseases
RNA Virus Infections
Respiratory Tract Diseases
Influenza

Interventions: Biological: Quadrivalent VLP Vaccine
Biological: Placebo

First Posted Date: 2017-10-04

Last Posted Date: 2023-08-14

Lead Sponsor: Medicago

Target Recruit Count: 10160

Registration Number: NCT03301051

Locations: 🇺🇸
Site 220, Hollywood, Florida, United States
🇺🇸
Site 201, Columbus, Ohio, United States
🇺🇸
Site 211, West Jordan, Utah, United States

and more 70 locations

Centralized Reminder Recall - Flu RCT2

Not Applicable

Completed

Conditions: Respiratory Tract Infections
Virus Disease
Vaccines
Physiological Effects of Drugs
Influenza, Human
Orthomyxoviridae Infections
RNA Virus Infections
Respiratory Tract Disease

Interventions: Behavioral: R/R - Texting
Behavioral: R/R - mailed postcard
Behavioral: R/R - Autodialers

First Posted Date: 2017-09-27

Last Posted Date: 2019-06-05

Lead Sponsor: University of California, Los Angeles

Target Recruit Count: 70190

Registration Number: NCT03294473

Locations: 🇺🇸
University of California, Los Angeles, Los Angeles, California, United States

Gene Transfer for Sickle Cell Disease

Phase 1

Active, not recruiting

Conditions: Sickle Cell Disease

Interventions: Biological: single infusion of autologous bone marrow derived CD34+ HSC cells transduced with the lentiviral vector containing a short-hairpin RNA targeting BCL11a

First Posted Date: 2017-09-14

Last Posted Date: 2024-07-09

Lead Sponsor: David Williams

Target Recruit Count: 10

Registration Number: NCT03282656

Locations: 🇺🇸
UCLA - Mattel Children's Hospital, Los Angeles, California, United States
🇺🇸
Boston Children's Hospital, Boston, Massachusetts, United States

RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2

Completed

Conditions: Cardiovascular Disease
Hypertension

First Posted Date: 2017-07-21

Last Posted Date: 2022-06-15

Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Target Recruit Count: 1700

Registration Number: NCT03225183

Locations: 🇺🇸
Framingham Heart Study, Framingham, Massachusetts, United States

Assessment of the Impact of RNA Genomic Profile on Treatment Decision-making in HER2 Equivocal Breast Cancer Patients

Not Applicable

Terminated

Conditions: Breast Cancer

Interventions: Diagnostic Test: PAM 50 test

First Posted Date: 2017-06-23

Last Posted Date: 2019-07-25

Lead Sponsor: Centre Jean Perrin

Target Recruit Count: 26

Registration Number: NCT03197805

Locations: 🇫🇷
CHRU Jean Minoz, Besançon, France
🇫🇷
Institut Bergonie, Bordeaux, France
🇫🇷
Centre François Baclesse, Caen, France

and more 13 locations

Long Non Coding RNA in Complications of Systemic Lupus

Not Applicable

Conditions: Complication in Systemic Lupus Erythematosus

Interventions: Other: blood sampling

First Posted Date: 2017-06-14

Last Posted Date: 2017-06-14

Lead Sponsor: Cairo University

Target Recruit Count: 100

Registration Number: NCT03185767

Locations: 🇪🇬
Cairo University, Cairo, Egypt

Specific Small RNA in Plasma for Predicting Diaphragm Dysfunction in Mechanically Ventilated Patients

Conditions: Mechanical Ventilation Complication

Interventions: Other: no Intervention

First Posted Date: 2017-06-01

Last Posted Date: 2017-06-06

Lead Sponsor: Southeast University, China

Target Recruit Count: 140

Registration Number: NCT03172169

Oxidative Stress-related Gene Expression in Cumulus Cells Among Low Responders

Conditions: Low Responder

Interventions: Diagnostic Test: Oxidative stress-related gene expression (RNA expression)
Diagnostic Test: oocyte competence biomarkers

First Posted Date: 2017-05-16

Last Posted Date: 2017-05-16

Lead Sponsor: Chulalongkorn University

Target Recruit Count: 56

Registration Number: NCT03155438

Locations: 🇹🇭
Faculty of Medicine ,Chulalongkorn University, Bangkok, Thailand

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