Overview
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Indication
For as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement and also used in prevention of angina.
Associated Conditions
- Coronary Artery Disease (CAD)
- Postoperative Thromboembolism
- Stroke
- Thrombosis
- Transient Ischemic Attack
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2025/02/13 | Phase 2 | Not yet recruiting | |||
2022/03/31 | Not Applicable | Completed | Northern Jiangsu People's Hospital | ||
2021/12/22 | Phase 2 | Terminated | |||
2020/12/14 | Phase 4 | Recruiting | Vastra Gotaland Region | ||
2020/11/27 | Phase 4 | Completed | Northern Jiangsu People's Hospital | ||
2020/06/11 | Phase 2 | Terminated | UConn Health | ||
2020/06/01 | Phase 3 | Completed | |||
2020/05/18 | Phase 2 | Completed | |||
2018/07/19 | Phase 1 | UNKNOWN | Henan University of Traditional Chinese Medicine | ||
2017/01/10 | N/A | Recruiting |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Amneal Pharmaceuticals of New York LLC | 0115-1070 | ORAL | 25 mg in 1 1 | 4/17/2023 | |
| Amneal Pharmaceuticals of New York LLC | 0115-1072 | ORAL | 75 mg in 1 1 | 4/17/2023 | |
| Sun Pharmaceutical Industries, Inc. | 47335-927 | ORAL | 200 mg in 1 1 | 1/18/2019 | |
| Micro Labs Limited | 42571-274 | ORAL | 200 mg in 1 1 | 11/28/2022 | |
| Zydus Lifesciences Limited | 70771-1172 | ORAL | 200 mg in 1 1 | 10/13/2022 | |
| Hikma Pharmaceuticals USA Inc. | 0641-2569 | INTRAVENOUS | 5 mg in 1 mL | 4/13/2022 | |
| Proficient Rx LP | 71205-896 | ORAL | 75 mg in 1 1 | 4/1/2022 | |
| Par Pharmaceutical, Inc. | 49884-007 | ORAL | 200 mg in 1 1 | 9/17/2018 | |
| Oxford Pharmaceuticals, LLC | 69584-181 | ORAL | 25 mg in 1 1 | 3/30/2021 | |
| Zydus Pharmaceuticals USA Inc. | 68382-188 | ORAL | 50 mg in 1 1 | 9/16/2023 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| PROCARDIN 75 TABLET 75 mg | SIN00263P | TABLET, FILM COATED | 75 mg | 4/6/1988 | |
| PERAZODIN 25 TABLET 25 mg | SIN00739P | TABLET, SUGAR COATED | 25 mg | 5/5/1988 | |
| PERAZODIN 75 TABLET 75 mg | SIN00470P | TABLET, SUGAR COATED | 75 mg | 4/27/1988 | |
| PERSANTIN INJECTION 10 mg/2 ml | SIN00206P | INJECTION | 10 mg/2 ml | 3/28/1988 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| Dipyridamole for Injection | 国药准字H20031355 | 化学药品 | 注射剂 | 8/31/2020 | |
| Dipyridamole for Injection | 国药准字H20031356 | 化学药品 | 注射剂 | 9/5/2020 | |
| Dipyridamole for Injection | 国药准字H20031357 | 化学药品 | 注射剂 | 9/5/2020 | |
| Dipyridamole for Injection | 国药准字H20050482 | 化学药品 | 注射剂 | 2/26/2021 | |
| Dipyridamole Dispersible Tablets | 国药准字H20050252 | 化学药品 | 片剂 | 9/1/2020 | |
| Dipyridamole Tablets | 国药准字H12020225 | 化学药品 | 片剂 | 9/2/2020 | |
| Dipyridamole Tablets | 国药准字H15020193 | 化学药品 | 片剂 | 3/29/2020 | |
| Dipyridamole Tablets | 国药准字H21022092 | 化学药品 | 片剂 | 8/26/2020 | |
| Dipyridamole Tablets | 国药准字H50020364 | 化学药品 | 片剂 | 9/24/2020 | |
| Dipyridamole Tablets | 国药准字H19993227 | 化学药品 | 片剂（糖衣片） | 9/17/2020 |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| PROCARDIN 75 TAB 75MG | N/A | N/A | N/A | 10/7/1991 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| DIPYRAMOLE SR Dipyridamole/Aspirin 200 mg/25 mg modified release capsules bottle | 210816 | Medicine | A | 5/9/2014 | |
| GenPar Dipyridamole/Aspirin SR Dipyridamole/Aspirin 200 mg/25 mg modified release capsules bottle | 210820 | Medicine | A | 5/9/2014 | |
| DIPYRASP SR Dipyridamole/Aspirin 200 mg/25 mg modified release capsules bottle | 210809 | Medicine | A | 5/9/2014 | |
| DIPYRIDAMOLE/ASPIRIN SR GxP Dipyridamole/Aspirin 200 mg/25 mg modified release capsules bottle | 210817 | Medicine | A | 5/9/2014 | |
| PERSANTIN dipyridamole 10mg/2mL injection ampoule | 17934 | Medicine | A | 9/26/1991 | |
| DIASPYRID SR Dipyridamole/Aspirin 200 mg/25 mg modified release capsules bottle | 210814 | Medicine | A | 5/9/2014 | |
| DIPYRIDAMOLE/ASPIRIN SR GPPL Dipyridamole/Aspirin 200 mg/25 mg modified release capsules bottle | 210815 | Medicine | A | 5/9/2014 |
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