Fluoxetine
- Generic Name
- Fluoxetine
- Brand Names
- Prozac, Sarafem, Symbyax
- Drug Type
- Small Molecule
- Chemical Formula
- C17H18F3NO
- CAS Number
- 54910-89-3
- Unique Ingredient Identifier
- 01K63SUP8D
- Background
Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
- Indication
Fluoxetine is indicated for both acute and maintenance treatment of major depressive disorder, obsessive compulsive disorder, and bulimia nervosa; however, it is only indicated for acute treatment of panic disorder independent of whether agoraphobia is present. Fluoxetine may also be used in combination with olanzapine to treat depression related to Bipolar ...
- Associated Conditions
- Alcohol Dependency, Anorexia Nervosa (AN), Bulimia Nervosa, Cataplexy, Depression, Major Depressive Disorder (MDD), Major depressive disorder, recurrent episode, Myoclonus, Obesity, Obsessive Compulsive Disorder (OCD), Panic Disorder With Agoraphobia, Panic disorder without agoraphobia, Premature Ejaculation, Premenstrual Dysphoric Disorder (PMDD)
- Associated Therapies
- Maintenance therapy
Safety and Efficacy of Vilazodone in Pediatric Patients With Major Depressive Disorder (VLZ-MD-22)
- Conditions
- Interventions
- First Posted Date
- 2015-02-26
- Last Posted Date
- 2019-10-01
- Lead Sponsor
- Forest Laboratories
- Target Recruit Count
- 473
- Registration Number
- NCT02372799
- Locations
- 🇺🇸
Harmonex Neuroscience Research, Dothan, Alabama, United States
🇺🇸Woodland International Research Group, INC, Little Rock, Arkansas, United States
🇺🇸ATP Clinical Research, Costa Mesa, California, United States
Fluoxetine vs Aripiprazole Comparative Trial (FACT)
- Conditions
- Interventions
- First Posted Date
- 2015-02-06
- Last Posted Date
- 2023-11-15
- Lead Sponsor
- Northwell Health
- Target Recruit Count
- 9
- Registration Number
- NCT02357849
- Locations
- 🇺🇸
The Zucker Hillside Hospital, Glen Oaks, New York, United States
Serotonin-norepinephrine Reuptake Inhibitors and Acute Kidney Injury
- First Posted Date
- 2014-12-19
- Last Posted Date
- 2016-03-14
- Target Recruit Count
- 3255526
- Registration Number
- NCT02320240
- Locations
- 🇨🇦
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada
Bupropion for Depression in ESRD Patients on Hemodialysis
- Conditions
- Interventions
- First Posted Date
- 2014-09-12
- Last Posted Date
- 2018-07-17
- Lead Sponsor
- University of Arkansas
- Target Recruit Count
- 1
- Registration Number
- NCT02238977
- Locations
- 🇺🇸
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
Effects rTMS Combined With Fluoxetine on Motor Recovery in Stroke Patients
- First Posted Date
- 2014-08-05
- Last Posted Date
- 2021-02-21
- Lead Sponsor
- Spaulding Rehabilitation Hospital
- Target Recruit Count
- 44
- Registration Number
- NCT02208466
- Locations
- 🇺🇸
Spaulding Rehabilitation Hospital, Charlestown, Massachusetts, United States
Comparison of Acupuncture and Fluoxetine on Quality of Life in Menopausal Women
- First Posted Date
- 2014-07-11
- Last Posted Date
- 2019-02-15
- Lead Sponsor
- Gonabad University of Medical Sciences
- Target Recruit Count
- 140
- Registration Number
- NCT02188225
- Locations
- 🇮🇷
Narjes Bahri, Mashhad, Razavi Hkorasan Privience, Iran, Islamic Republic of
🇮🇷Gonabad University of Medical Sciences, Gonabad, Khorasan Razavi, Iran, Islamic Republic of
"Evaluation by Transcranial Magnetic Stimulation of the Benefit of Fluoxetine on Motor Recovery After Stroke"
- Conditions
- Interventions
- First Posted Date
- 2014-02-14
- Last Posted Date
- 2017-10-20
- Lead Sponsor
- Centre Hospitalier St Anne
- Target Recruit Count
- 6
- Registration Number
- NCT02063425
- Locations
- 🇫🇷
Centre Hospitalier Sainte-Anne, Paris, France
Efficacy of Exposure and Response Prevention(ERP) and SSRIs in Chinese OCD Patients
- First Posted Date
- 2013-12-30
- Last Posted Date
- 2022-09-09
- Lead Sponsor
- Shanghai Mental Health Center
- Target Recruit Count
- 78
- Registration Number
- NCT02022709
- Locations
- 🇨🇳
Shanghai Mental Health Center, Shanghai, Shanghai, China
An Adaptive Treatment Strategy for Adolescent Depression-Continuation
- Conditions
- Interventions
- First Posted Date
- 2013-12-20
- Last Posted Date
- 2020-03-23
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 15
- Registration Number
- NCT02017535
- Locations
- 🇺🇸
University of Minnesota, Department of Psychiatry, Minneapolis, Minnesota, United States
A Study of the Effect of Multiple Doses of Itraconazole and Fluoxetine on the Pharmacokinetics of a Single Dose of RO5285119 in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2013-10-23
- Last Posted Date
- 2016-11-02
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 28
- Registration Number
- NCT01967979
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.