Furazolidone

Generic Name
Furazolidone
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C8H7N3O5
CAS Number
67-45-8
Unique Ingredient Identifier
5J9CPU3RE0
Background

A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)

Indication

For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.

Associated Conditions
Diarrhea (Dysentery), Infectious diarrhea
Associated Therapies
-

Helicobacter Rescue Therapy With Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy

First Posted Date
2023-12-13
Last Posted Date
2024-07-30
Lead Sponsor
Yongquan Shi
Target Recruit Count
688
Registration Number
NCT06168084
Locations
🇨🇳

Xijing Hosipital of Digestive Disease, Xi'an, Shanxi, China

Efficacy of Therapy Based on Fecal Molecular Antimicrobial Susceptibility Tests for Helicobacter Pylori Infection

First Posted Date
2023-02-08
Last Posted Date
2023-05-15
Lead Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Target Recruit Count
855
Registration Number
NCT05718609
Locations
🇨🇳

Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China

Helicobacter Pylori Rescue Treatment in Patients Allergic to Penicillin

First Posted Date
2021-11-26
Last Posted Date
2021-11-30
Lead Sponsor
Shandong University
Target Recruit Count
170
Registration Number
NCT05135182
Locations
🇨🇳

Qilu hosipital, Jinan, Shandong, China

Efficacy and Safety of Vonoprazan as First-line Treatment for Helicobacter Pylori Eradication

First Posted Date
2021-06-01
Last Posted Date
2021-06-01
Lead Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
Target Recruit Count
234
Registration Number
NCT04907747
Locations
🇨🇳

Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China

Helicobacter Rescue Therapy With High-dose Esomeprazole and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy

First Posted Date
2020-12-22
Last Posted Date
2023-01-31
Lead Sponsor
Xijing Hospital of Digestive Diseases
Target Recruit Count
658
Registration Number
NCT04678492
Locations
🇨🇳

Xijing Hosipital of Digestive Disease, Xi'an, Shaanxi, China

Helicobacter Pylori Rescue Treatment Containing Tetracycline in Patients Allergic to Penicillin

First Posted Date
2020-02-11
Last Posted Date
2021-11-18
Lead Sponsor
Shandong University
Target Recruit Count
250
Registration Number
NCT04264663
Locations
🇨🇳

Qilu hospital, Jinan, Shandong, China

A Comparison of Clarithromycin-based and Furazolidone-based Bismuth-containing Regimens for H. Pylori Eradication

Phase 4
Completed
Conditions
Interventions
First Posted Date
2018-10-23
Last Posted Date
2020-06-23
Lead Sponsor
Shandong University
Target Recruit Count
350
Registration Number
NCT03716622
Locations
🇨🇳

Qilu hosipital, Jinan, Shandong, China

Doxycycline- and Furazolidone-containing Quadruple Regimen is Superior of Tailored Therapy

First Posted Date
2016-09-09
Last Posted Date
2018-09-05
Lead Sponsor
Sir Run Run Shaw Hospital
Target Recruit Count
300
Registration Number
NCT02894268
Locations
🇨🇳

Sir Run Run Shaw Hospital,Zhejiang University, Hangzhou, Zhejiang, China

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