Vancomycin

Generic Name
Vancomycin
Brand Names
Firvanq, Vancocin
Drug Type
Small Molecule
Chemical Formula
C66H75Cl2N9O24
CAS Number
1404-90-6
Unique Ingredient Identifier
6Q205EH1VU
Background

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.
...

Indication

Administered intravenously, vancomycin is indicated in adult and pediatric patients for the treatment of septicemia, infective endocarditis, skin and skin structure infections, bone infections, and lower respiratory tract infections. Administered orally, vancomycin is indicated in adult and pediatric patients for the treatment of Clostridium difficile-associ...

Associated Conditions
Clostridium Difficile Associated Diarrhea (CDAD), Enterocolitis caused by Staphylococcus aureus, Infection caused by staphylococci, Severe Staphylococcal infection
Associated Therapies
-

Vancomycin Pharmacokinetics in Patients on Peritoneal Dialysis

Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-09-26
Last Posted Date
2022-03-03
Lead Sponsor
Thomas Jefferson University
Target Recruit Count
4
Registration Number
NCT03685747
Locations
🇺🇸

Thomas Jefferson University, Philadelphia, Pennsylvania, United States

Topical Antibiotics in Chronic Rhinosinusitis

First Posted Date
2018-09-17
Last Posted Date
2022-04-20
Lead Sponsor
Mayo Clinic
Target Recruit Count
19
Registration Number
NCT03673956
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Comparison of Ridinilazole Versus Vancomycin Treatment for Clostridium Difficile Infection

First Posted Date
2018-07-23
Last Posted Date
2023-03-03
Lead Sponsor
Summit Therapeutics
Target Recruit Count
759
Registration Number
NCT03595553
Locations
🇧🇬

DCC1-Sliven Ltd., Sliven, Bulgaria

🇬🇷

''Tzaneio'' General Hospital of Piraeus, Piraeus, Greece

🇭🇺

Dr. Kenessey Albert Kórház Rendelőintézet, Tüdőgyógyászati Aktív Osztály, Balassagyarmat, Hungary

and more 146 locations

Vancomycin in the Target Site Treatment of Intracranial Infection

Phase 4
Conditions
Interventions
First Posted Date
2018-07-13
Last Posted Date
2018-07-13
Lead Sponsor
Xijing Hospital
Target Recruit Count
2
Registration Number
NCT03585426

Responses to Rabies Vaccine in Adults With or Without Antibiotics

First Posted Date
2018-06-14
Last Posted Date
2023-06-08
Lead Sponsor
Emory University
Target Recruit Count
37
Registration Number
NCT03557008
Locations
🇺🇸

Winship Cancer Institute of Emory University, Atlanta, Georgia, United States

🇺🇸

The Hope Clinic of the Emory Vaccine Center, Decatur, Georgia, United States

Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

First Posted Date
2018-06-06
Last Posted Date
2024-07-30
Lead Sponsor
Abramson Cancer Center at Penn Medicine
Target Recruit Count
10
Registration Number
NCT03546829
Locations
🇺🇸

University of Pennsylvania, Philadelphia, Pennsylvania, United States

Regional Prophylactic Vancomycin With Restricted Tourniquet Time in Primary Total Knee Replacement

Phase 2
Completed
Conditions
Interventions
First Posted Date
2018-04-24
Last Posted Date
2020-01-27
Lead Sponsor
Mayo Clinic
Target Recruit Count
24
Registration Number
NCT03506347
Locations
🇺🇸

Mayo Clinic in Arizona, Scottsdale, Arizona, United States

Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease

First Posted Date
2018-03-26
Last Posted Date
2022-02-09
Lead Sponsor
Children's Hospital of Philadelphia
Target Recruit Count
10
Registration Number
NCT03476317
Locations
🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

The Effectiveness of Vancomycin in Comarison With Cefazolin in Prevention of SSI After Craniotomy

First Posted Date
2018-03-15
Last Posted Date
2018-03-15
Lead Sponsor
Isfahan University of Medical Sciences
Target Recruit Count
126
Registration Number
NCT03466645
Locations
🇮🇷

Isfahan university of medical science., Isfahan, Iran, Islamic Republic of

Efficacy of Oral Vancomycin Prophylaxis for Prevention of Recurrent Clostridium Difficile Infection

First Posted Date
2018-03-12
Last Posted Date
2023-07-28
Lead Sponsor
University of Wisconsin, Madison
Target Recruit Count
77
Registration Number
NCT03462459
Locations
🇺🇸

Medical College of Wisconsin, Milwaukee, Wisconsin, United States

🇺🇸

University of Wisconsin-Madison, Madison, Wisconsin, United States

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