MedPath

Vancomycin

Generic Name
Vancomycin
Brand Names
Firvanq, Vancocin
Drug Type
Small Molecule
Chemical Formula
C66H75Cl2N9O24
CAS Number
1404-90-6
Unique Ingredient Identifier
6Q205EH1VU

Overview

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains [LP1196]. Such an oral liquid formulation is expected to make Clostridium difficile associated diarrhea therapy more accessible in comparison to previously available specialty compounding products [LP1196].

Background

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains [LP1196]. Such an oral liquid formulation is expected to make Clostridium difficile associated diarrhea therapy more accessible in comparison to previously available specialty compounding products [LP1196].

Indication

Administered intravenously, vancomycin is indicated in adult and pediatric patients for the treatment of septicemia, infective endocarditis, skin and skin structure infections, bone infections, and lower respiratory tract infections. Administered orally, vancomycin is indicated in adult and pediatric patients for the treatment of Clostridium difficile-associated diarrhea and for enterocolitis caused by Staphylococcus aureus (including methicillin-resistant strains).

Associated Conditions

  • Clostridium Difficile Associated Diarrhea (CDAD)
  • Enterocolitis caused by Staphylococcus aureus
  • Infection caused by staphylococci
  • Severe Staphylococcal infection

FDA Approved Products

Vancomycin Hydrochloride
Manufacturer:Fresenius Kabi USA, LLC
Route:INTRAVENOUS
Strength:5 g in 100 mL
Approved: 2021/04/26
NDC:63323-295
Vancomycin Hydrochloride
Manufacturer:Xellia Pharmaceuticals USA LLC
Route:INTRAVENOUS
Strength:500 mg in 1 1
Approved: 2023/12/12
NDC:70594-122
vancomycin hydrochloride
Manufacturer:Alvogen Inc.
Route:ORAL
Strength:250 mg in 1 1
Approved: 2012/04/12
NDC:47781-730
Vancomycin Hydrochloride
Manufacturer:Hospira, Inc.
Route:INTRAVENOUS
Strength:500 mg in 1 1
Approved: 2023/08/07
NDC:0409-4332
VANCOMYCIN HYDROCHLORIDE
Manufacturer:Slate Run Pharmaceuticals, LLC
Route:INTRAVENOUS
Strength:5 g in 1 1
Approved: 2021/11/26
NDC:70436-022

Singapore Approved Products

No Singapore products found for this drug

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