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Favipiravir

Generic Name
Favipiravir
Drug Type
Small Molecule
Chemical Formula
C5H4FN3O2
CAS Number
259793-96-9
Unique Ingredient Identifier
EW5GL2X7E0

Overview

Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza. The antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and replication of viral genomes. Not only does favipiravir inhibit replication of influenza A and B, but the drug has shown promise in the treatment of avian influenza, and may be an alternative option for influenza strains that are resistant to neuramidase inhibitors. Favipiravir has been investigated for the treatment of life-threatening pathogens such as Ebola virus, Lassa virus, and now COVID-19.

Background

Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza. The antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and replication of viral genomes. Not only does favipiravir inhibit replication of influenza A and B, but the drug has shown promise in the treatment of avian influenza, and may be an alternative option for influenza strains that are resistant to neuramidase inhibitors. Favipiravir has been investigated for the treatment of life-threatening pathogens such as Ebola virus, Lassa virus, and now COVID-19.

Indication

⑴用于埃博拉病毒感染的治疗。 ⑵用于治疗成人新型或再次流行的流感(仅限于其他抗流感病毒药物治疗无效或效果不佳时使用)

Associated Conditions

  • Treatment resistant Novel Influenza
  • Treatment resistant Reemerging Influenza

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

No Singapore products found for this drug

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