Tisagenlecleucel

Generic Name
Tisagenlecleucel
Brand Names
Kymriah
Drug Type
Biotech
Chemical Formula
-
CAS Number
1823078-37-0
Unique Ingredient Identifier
Q6C9WHR03O
Background

Tisagenlecleucel is a CD19-directed genetically modified autologous T cell immunotherapy, or a CAR-T cell therapy for B-cell acute lymphoblastic leukemia. It was granted approval by FDA in August 2017 under the market name Kymriah. Tisagenlecleucel is an immunocellular therapy that involves autologous T cells that are collected from each individual patient a...

Indication

Tisagenlecleucel is indicated for use in individuals aged 25 years and younger with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory or in second or later relapse.
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Associated Conditions
Refractory Diffuse Large B Cell Lymphoma (DLBCL), Refractory Follicular Lymphoma, Relapsed Diffuse Large B-cell Lymphoma (DLBCL), Relapsed Follicular Lymphoma, Refractory B-cell precursor acute lymphoblastic leukemia, Relapsed B cell precursor Acute lymphoblastic leukemia
Associated Therapies
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