MedPath

Belladonna

Generic Name
Belladonna
Drug Type
Biotech
Unique Ingredient Identifier
WQZ3G9PF0H

Overview

Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in the nightshade family Solanaceae. Its roots, leaves and fruits contain Hyoscyamine, Scopolamine, and mostly, Atropine. These alkaloids are naturally-occurring muscarinic antagonists. Atropine is a non-selective muscarinic antagonist that is mainly used as an adjunct for anaesthesia. The name "belladonna" originates from the Italian words "beautiful woman" and the historical use of herb eye-drops by women to dilate the pupils of the eyes for aesthetic purposes. Belladonna is a poisonous plant and belladonna intoxication from accidental ingestion may result in a severe anticholinergic syndrome, which is associated with both central and peripheral manifestations .

Background

Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in the nightshade family Solanaceae. Its roots, leaves and fruits contain Hyoscyamine, Scopolamine, and mostly, Atropine. These alkaloids are naturally-occurring muscarinic antagonists. Atropine is a non-selective muscarinic antagonist that is mainly used as an adjunct for anaesthesia. The name "belladonna" originates from the Italian words "beautiful woman" and the historical use of herb eye-drops by women to dilate the pupils of the eyes for aesthetic purposes. Belladonna is a poisonous plant and belladonna intoxication from accidental ingestion may result in a severe anticholinergic syndrome, which is associated with both central and peripheral manifestations .

Indication

No therapeutic indications.

Associated Conditions

  • Bloating
  • Heartburn
  • Menopausal Symptoms
  • Poisoning of the Intestine
  • Poisoning of the Stomach
  • Reflux Acid
  • Belching
  • Gastrointestinal spasms

Clinical Trials

FDA Approved Products

Belladonna and Opium
Manufacturer:Bryant Ranch Prepack
Route:RECTAL
Strength:16.2 mg in 1 1
Approved: 2021/06/01
NDC:63629-8436
Belladonna and Opium
Manufacturer:Padagis US LLC
Route:RECTAL
Strength:16.2 mg in 1 1
Approved: 2018/08/08
NDC:0574-7045
Belladonna and Opium
Manufacturer:Padagis US LLC
Route:RECTAL
Strength:16.2 mg in 1 1
Approved: 2018/08/08
NDC:0574-7040
StressCalm
Manufacturer:Boiron
Route:ORAL
Strength:6 [hp_C] in 1 1
Approved: 2025/03/21
NDC:0220-9333
BELLADONNA 30C - 3-Pack
Manufacturer:SEVENE USA
Route:SUBLINGUAL
Strength:30 [hp_C] in 1 1
Approved: 2025/05/15
NDC:76472-5001

Singapore Approved Products

No Singapore products found for this drug

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