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Belladonna

Generic Name
Belladonna
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
WQZ3G9PF0H
Background

Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in the nightshade family Solanaceae. Its roots, leaves and fruits contain Hyoscyamine, Scopolamine, and mostly, Atropine. These alkaloids are naturally-occurring muscarinic antagonists. Atropine is a non-selective muscarinic antagonist that is mainly used as an adjunct for anaesthesia. The name "belladonna" originates from the Italian words "beautiful woman" and the historical use of herb eye-drops by women to dilate the pupils of the eyes for aesthetic purposes. Belladonna is a poisonous plant and belladonna intoxication from accidental ingestion may result in a severe anticholinergic syndrome, which is associated with both central and peripheral manifestations .

Indication

No therapeutic indications.

Associated Conditions
Bloating, Heartburn, Menopausal Symptoms, Poisoning of the Intestine, Poisoning of the Stomach, Reflux Acid, Belching, Gastrointestinal spasms
Associated Therapies
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nature.com
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Herbal extracts in orofacial pain: a systematic review and direct and indirect meta-analysis

7709 studies identified, 62 included after deduplication and assessment. Most studies were blinded with sample sizes ranging from 15 to 270 patients. 70 different plants from 44 families were identified. Risk of bias assessment showed 27 studies with concerns, 22 with low risk, and 13 with high risk. 62 papers identified 17 orofacial pain conditions categorized into six groups. Meta-analyses found herbal extracts more effective in reducing periodontal, oral surgery, oral neuropathic, endodontic, oral mucosal, and TMD pain compared to standard therapies.
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