Prasterone

Generic Name
Prasterone
Brand Names
Intrarosa
Drug Type
Small Molecule
Chemical Formula
C19H28O2
CAS Number
53-43-0
Unique Ingredient Identifier
459AG36T1B
Background

Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion....

Indication

DHEA is taken as a supplement for a variety of unsubstantiated indications. The following indications have shown promise and are backed up by some scientific evidence: schizophrenia (DHEA may be more effective in women than men); improving the appearance of older people’s skin (taking DHEA by mouth seems to increase skin thickness and moisture, and decrease ...

Associated Conditions
Moderate Dyspareunia, Severe Dyspareunia
Associated Therapies
-

Investigating Novel Interventions for Low Back Pain in US Military Veterans: A Randomized Controlled Adaptive Phase II Trial

Phase 2
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-07-07
Last Posted Date
2024-04-05
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
108
Registration Number
NCT05935761
Locations
🇺🇸

Durham VA Medical Center, Durham, NC, Durham, North Carolina, United States

The Effect of Myo-inositol, Somatropin, and DHEA on Poor Ovarian Responders

First Posted Date
2023-06-12
Last Posted Date
2023-07-18
Lead Sponsor
Beni-Suef University
Target Recruit Count
300
Registration Number
NCT05900661
Locations
🇪🇬

Beni-suef university Hospital, Banī Suwayf, Beni Suef, Egypt

GRACE-trial: a Randomized Active-controlled Trial for vulvovaGinal atRophy in breAst Cancer Patients on Endocrine Therapy.

First Posted Date
2022-09-30
Last Posted Date
2023-09-29
Lead Sponsor
University Hospital, Ghent
Target Recruit Count
160
Registration Number
NCT05562518
Locations
🇧🇪

University Hospital Ghent, Gent, Belgium

Does DHEA IVF Outcomes in Poor Responders?

First Posted Date
2019-08-26
Last Posted Date
2022-06-23
Lead Sponsor
Homerton University Hospital NHS Foundation Trust
Target Recruit Count
400
Registration Number
NCT04066478
Locations
🇬🇧

Homerton Fertility Centre, London, United Kingdom

Clinical Trial on the Preventive Effect of Intravaginal Prasterone on Recurrent Urinary Tract Infections in Postmenopausal Women

First Posted Date
2019-02-26
Last Posted Date
2021-06-30
Lead Sponsor
Olivia Cardenas-Trowers, M.D.
Registration Number
NCT03854396
Locations
🇺🇸

University of Louisville Urogynecology at Springs Medical Center, Louisville, Kentucky, United States

Changes to Vulva, Vestibule, Urethral Meatus and Vagina 20 Weeks Post Daily Prasterone in Women With Dyspareunia

Phase 4
Completed
Conditions
Interventions
First Posted Date
2018-06-26
Last Posted Date
2022-06-09
Lead Sponsor
San Diego Sexual Medicine
Target Recruit Count
18
Registration Number
NCT03568604
Locations
🇺🇸

San Diego Sexual Medicine, San Diego, California, United States

Neurosteroids in PTSD - Biomarkers to Therapeutics

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2018-04-06
Last Posted Date
2023-05-06
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
5
Registration Number
NCT03491007
Locations
🇺🇸

Durham VA Medical Center, Durham, NC, Durham, North Carolina, United States

The Effects of Fluoxetine And/or DHEA

First Posted Date
2017-07-25
Last Posted Date
2024-11-05
Lead Sponsor
University of Maryland, Baltimore
Target Recruit Count
60
Registration Number
NCT03228732
Locations
🇺🇸

University of Maryland, Baltimore, Maryland, United States

Dehydroepiandrosterone (DHEA)Supplementation Pre-IVF(In Vitro Fertilization) Cycles

Phase 4
Completed
Conditions
Interventions
First Posted Date
2016-08-15
Last Posted Date
2019-09-19
Lead Sponsor
ShangHai Ji Ai Genetics & IVF Institute
Target Recruit Count
78
Registration Number
NCT02866253

Combined Dehydropeiandrosterone and Growth Hormone in Women With Expected Poor Ovarian Response Undergoing ICSI

First Posted Date
2016-05-10
Last Posted Date
2018-01-03
Lead Sponsor
Cairo University
Target Recruit Count
230
Registration Number
NCT02766764
Locations
🇪🇬

Cairo university hospitals, Cairo, Egypt

🇪🇬

Dar AlTeb subfertility centre, Cairo, Egypt

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