Prasterone

Generic Name
Prasterone
Brand Names
Intrarosa
Drug Type
Small Molecule
Chemical Formula
C19H28O2
CAS Number
53-43-0
Unique Ingredient Identifier
459AG36T1B
Background

Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion....

Indication

DHEA is taken as a supplement for a variety of unsubstantiated indications. The following indications have shown promise and are backed up by some scientific evidence: schizophrenia (DHEA may be more effective in women than men); improving the appearance of older people’s skin (taking DHEA by mouth seems to increase skin thickness and moisture, and decrease ...

Associated Conditions
Moderate Dyspareunia, Severe Dyspareunia
Associated Therapies
-

Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on Fatigue

First Posted Date
2007-10-12
Last Posted Date
2007-11-04
Lead Sponsor
University of Helsinki
Target Recruit Count
107
Registration Number
NCT00543166
Locations
🇫🇮

Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland

Dehydroepiandrosterone (DHEA) and Letrozole in Treating Patients With Metastatic Breast Cancer

Phase 1
Terminated
Conditions
First Posted Date
2007-08-15
Last Posted Date
2012-07-24
Lead Sponsor
OHSU Knight Cancer Institute
Target Recruit Count
6
Registration Number
NCT00516542
Locations
🇺🇸

Knight Cancer Institute at Oregon Health and Science University, Portland, Oregon, United States

Does DHEA Enhance the Effects of Exercise in Postmenopausal Women?

Not Applicable
Completed
Conditions
First Posted Date
2007-02-14
Last Posted Date
2011-03-23
Lead Sponsor
Mayo Clinic
Target Recruit Count
32
Registration Number
NCT00434915
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

DHEA Bioavailability Following Administration of Vaginal Suppositories in Post-Menopausal Women With Vaginal Atrophy

Phase 1
Completed
Conditions
Interventions
First Posted Date
2007-02-01
Last Posted Date
2017-04-07
Lead Sponsor
CHU de Quebec-Universite Laval
Target Recruit Count
40
Registration Number
NCT00429806
Locations
🇨🇦

Clinique des traitements hormonaux CHUL Research Center, Quebec, Canada

Dehydroepiandrosterone Administration in Women With Systemic Lupus Erythematosus or Primary Sjögren's Syndrome

First Posted Date
2006-10-25
Last Posted Date
2006-10-25
Lead Sponsor
UMC Utrecht
Target Recruit Count
120
Registration Number
NCT00391924
Locations
🇳🇱

University Medical Center Groningen, Groningen, Netherlands

🇳🇱

University Medical Center Utrecht, Utrecht, Netherlands

Efficacy and Safety of Oral DHEA Therapy for Postmenopausal Women on Sexual Function, Wellbeing and Vasomotor Symptoms

First Posted Date
2006-02-10
Last Posted Date
2016-03-16
Lead Sponsor
Monash University
Target Recruit Count
240
Registration Number
NCT00289926
Locations
🇦🇺

Women's Health Research Program, Monash University, The Alfred Hospital, Melbourne, Victoria, Australia

Effect of DHEA on Skin Aging in Postmenopausal Women

First Posted Date
2005-11-04
Last Posted Date
2017-04-07
Lead Sponsor
CHU de Quebec-Universite Laval
Target Recruit Count
150
Registration Number
NCT00248989
Locations
🇨🇦

Clinique des Traitements Hormonaux- CHUL Research Center, Sainte-Foy, Quebec, Canada

Effects of DHEA and Exercise in the Elderly

Phase 3
Completed
Conditions
First Posted Date
2005-09-20
Last Posted Date
2006-01-06
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
64
Registration Number
NCT00205686
Locations
🇺🇸

Washington University School of Medicine, St. Louis, Missouri, United States

ANDRO 2002: Dehydroepiandrosterone (DHEA) or Testosterone Versus Placebo in Men With Sexual Dysfunction

Phase 2
Completed
Conditions
First Posted Date
2005-09-20
Last Posted Date
2016-01-13
Lead Sponsor
Queen's University
Target Recruit Count
120
Registration Number
NCT00202163
Locations
🇨🇦

Centre for Advanced Urological Research, Kingston, Ontario, Canada

Biological Effects of Dehydroepiandrosterone (DHEA) in the Elderly

Not Applicable
Completed
Conditions
First Posted Date
2005-05-27
Last Posted Date
2009-12-11
Lead Sponsor
National Institute on Aging (NIA)
Target Recruit Count
144
Registration Number
NCT00111930
Locations
🇺🇸

University of Colorado at Denver and Health Sciences Center, Denver, Colorado, United States

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