Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic aci...
Etidronate is indicated to treat Paget's disease of bone, as well as the treatment and prevention of heterotropic ossification after total hip replacement of spinal cord injury.
University Medical Center Utrecht, Utrecht, Netherlands
University Medical Center Utrecht, Utrecht, Netherlands
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
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