Etidronic acid

Generic Name
Etidronic acid
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C2H8O7P2
CAS Number
2809-21-4
Unique Ingredient Identifier
M2F465ROXU
Background

Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic aci...

Indication

Etidronate is indicated to treat Paget's disease of bone, as well as the treatment and prevention of heterotropic ossification after total hip replacement of spinal cord injury.

Associated Conditions
Heterotopic Ossification (HO), Paget's Disease of Bone
Associated Therapies
-

The Prevention of Systemic Ectopic Mineralization in Pseudoxanthoma Elasticum

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2023-04-27
Last Posted Date
2023-04-27
Lead Sponsor
UMC Utrecht
Target Recruit Count
76
Registration Number
NCT05832580
Locations
🇳🇱

University Medical Center Utrecht, Utrecht, Netherlands

Treatment of Ectopic Calcification in Fahr's Disease or Syndrome

First Posted Date
2022-12-22
Last Posted Date
2024-05-14
Lead Sponsor
UMC Utrecht
Target Recruit Count
98
Registration Number
NCT05662111
Locations
🇳🇱

University Medical Center Utrecht, Utrecht, Netherlands

Etidronate for Arterial Calcifications Due to Deficiency in CD73 (ACDC)

First Posted Date
2012-04-25
Last Posted Date
2022-10-04
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Target Recruit Count
7
Registration Number
NCT01585402
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

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