MedPath

Alfuzosin

Generic Name
Alfuzosin
Brand Names
Uroxatral, Xatral
Drug Type
Small Molecule
Chemical Formula
C19H27N5O4
CAS Number
81403-80-7
Unique Ingredient Identifier
90347YTW5F

Overview

Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to 80%-90% of those over 70. Alfuzosin is an alpha-1 adrenergic blocker used in the symptomatic treatment of BPH that works by relaxing the muscles in the prostate and bladder neck. It was initially approved by the FDA in 2003 and is marketed by several pharmaceutical companies.

Background

Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to 80%-90% of those over 70. Alfuzosin is an alpha-1 adrenergic blocker used in the symptomatic treatment of BPH that works by relaxing the muscles in the prostate and bladder neck. It was initially approved by the FDA in 2003 and is marketed by several pharmaceutical companies.

Indication

Alfuzosin is used to treat the signs and symptoms of benign prostatic hyperplasia (BPH).

Associated Conditions

  • Benign Prostatic Hyperplasia (BPH)

FDA Approved Products

Alfuzosin hydrochloride
Manufacturer:Liberty Pharmaceuticals, Inc.
Route:ORAL
Strength:10 mg in 1 1
Approved: 2016/08/09
NDC:0440-5000
Alfuzosin hydrochloride
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:10 mg in 1 1
Approved: 2022/05/06
NDC:63629-7907
Alfuzosin Hydrochloride
Manufacturer:Northwind Pharmaceuticals, LLC
Route:ORAL
Strength:10 mg in 1 1
Approved: 2023/01/23
NDC:51655-432
Alfuzosin hydrochloride
Manufacturer:Exelan Pharmaceuticals Inc.
Route:ORAL
Strength:10 mg in 1 1
Approved: 2022/12/01
NDC:76282-302
Alfuzosin Hydrochloride
Manufacturer:Aphena Pharma Solutions - Tennessee, LLC
Route:ORAL
Strength:10 mg in 1 1
Approved: 2017/07/25
NDC:43353-746

Singapore Approved Products

APO-ALFUZOSIN PROLONGED RELEASE TABLET 10mg
Manufacturer:Apotex Inc (Signet), Apotex Inc (Weston Road) (Primary and Secondary Packager)
Form:TABLET, EXTENDED RELEASE
Strength:10mg
Online:Yes
Approved: 2018/07/19
Approval:SIN15512P
Alfuzosin PH&T 10mg prolonged-release tablets
Manufacturer:MIPHARM S.P.A
Form:TABLET, EXTENDED RELEASE
Strength:10.000 mg
Online:Yes
Approved: 2010/06/21
Approval:SIN13819P
RANFUZOSIN MODIFIED RELEASE TABLETS 10MG
Manufacturer:SUN PHARMACEUTICAL INDUSTRIES LIMITED
Form:TABLET, EXTENDED RELEASE
Strength:10mg
Online:Yes
Approved: 2011/07/05
Approval:SIN13984P
XATRAL XL TABLET 10 mg
Manufacturer:SANOFI WINTHROP INDUSTRIE
Form:TABLET
Strength:10 mg
Online:Yes
Approved: 2001/07/05
Approval:SIN11579P
XATRAL SR TABLET 5 mg
Manufacturer:SANOFI WINTHROP INDUSTRIE
Form:TABLET, EXTENDED RELEASE
Strength:5 mg
Online:Yes
Approved: 1997/11/21
Approval:SIN09546P

Drug Development Updates

Stay informed with timely notifications on clinical trials and research advancements.

© Copyright 2025. All Rights Reserved by MedPath