卡贝缩宫素 (Duratocin)

概览

Carbetocin is an oxytocin agent used to control postpartum hemorrhage and bleeding after giving birth.

作用机制

Carbetocin binds to oxytocin receptors present on the smooth musculature of the uterus, resulting in rhythmic contractions of the uterus, increased frequency of existing contractions, and increased uterine tone. The oxytocin receptor content of the uterus is very low in the non-pregnant state, and increases during pregnancy, reaching a peak at the time of delivery.

适应症

Used to control postpartum hemorrhage and bleeding after giving birth.

• Postpartum Haemorrhage (PPH)
• Uterine Atony