MedPath

Carbetocin

Generic Name
Carbetocin
Brand Names
Duratocin
Drug Type
Small Molecule
Chemical Formula
C45H69N11O12S
CAS Number
37025-55-1
Unique Ingredient Identifier
88TWF8015Y
Background

Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.

Indication

Used to control postpartum hemorrhage and bleeding after giving birth.

Associated Conditions
Postpartum Haemorrhage (PPH), Uterine Atony

Carbetocin Versus Syntometrine in Obese Women Undergoing Elective Cesarean

Phase 4
Completed
Conditions
Post Partum Hemorrhage
Interventions
Drug: Syntometrine
First Posted Date
2018-10-03
Last Posted Date
2020-01-03
Lead Sponsor
Cairo University
Target Recruit Count
1200
Registration Number
NCT03693599
Locations
🇪🇬

faculty of medicine Cairo university, Giza, Egypt

Carbetocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With BMI ≥ 40kg/m2

Not Applicable
Completed
Conditions
Postpartum Hemorrhage
Interventions
First Posted Date
2018-09-14
Last Posted Date
2019-06-07
Lead Sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Target Recruit Count
30
Registration Number
NCT03672045
Locations
🇨🇦

Mount Sinai Hospital, Toronto, Ontario, Canada

Oxytocin i.m./i.v. Versus Carbetocin i.v. in Elective Cesarean Sections

Phase 4
Completed
Conditions
Postpartum Hemorrhage
Interventions
First Posted Date
2018-08-29
Last Posted Date
2023-05-24
Lead Sponsor
University of Zurich
Target Recruit Count
550
Registration Number
NCT03651882
Locations
🇨🇭

University Hospital Zurich, Zürich, Switzerland

Carbetocin Versus Oxytocin and Ergometrine for the Prevention of Postpartum Hemorrhage

Not Applicable
Completed
Conditions
Cesarean Section Complications
Interventions
First Posted Date
2018-07-06
Last Posted Date
2020-08-05
Lead Sponsor
Aswan University Hospital
Target Recruit Count
220
Registration Number
NCT03578263
Locations
🇪🇬

AswanUH, Aswan, Egypt

CARBETOCIN VERSUS RECTAL MISOPROSTOL FOR MANAGEMENT OF THIRD STAGE OF LABOR IN WOMEN AT LOW RISK OF POSTPARTUM HEMORRHAGE

Phase 4
Completed
Conditions
Postpartum Hemorrhage
Interventions
First Posted Date
2018-06-14
Last Posted Date
2019-10-11
Lead Sponsor
Cairo University
Target Recruit Count
150
Registration Number
NCT03556852
Locations
🇪🇬

Kasr Alainy medical school, Cairo, Egypt

Impact of Carbetocin Administration on Heart Rate When Given as an Infusion Versus as a Bolus.

Phase 4
Completed
Conditions
Cesarean Section Complications
Hemodynamic Instability
Interventions
First Posted Date
2018-01-19
Last Posted Date
2021-10-04
Lead Sponsor
Ciusss de L'Est de l'Île de Montréal
Target Recruit Count
70
Registration Number
NCT03404544
Locations
🇨🇦

CIUSSS de l'Est de l'Ile de Montreal, Montreal, Quebec, Canada

Carbetocin vs. Oxytocin at Elective Cesarean Section

Not Applicable
Completed
Conditions
Postpartum Hemorrhage
Interventions
First Posted Date
2017-05-30
Last Posted Date
2021-03-03
Lead Sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Target Recruit Count
278
Registration Number
NCT03168698
Locations
🇨🇦

Mount Sinai Hospital, Toronto, Ontario, Canada

🇨🇦

McMaster University Medical Centre (MUMC), Hamilton, Ontario, Canada

Early Usage of Bakri Ballon in Managing Postpartum Hemorrhage

Not Applicable
Completed
Conditions
Postpartum Hemorrhage
Interventions
Device: Bakri Balloon
Procedure: Uterine Massage
Procedure: B-lynch Suture
Procedure: Uterine Artery Embolization using sponges
Procedure: Cervical cerclage
Procedure: Hysterectomy
Drug: Blood Product
First Posted Date
2016-08-10
Last Posted Date
2016-12-16
Lead Sponsor
Dongyu Wang
Target Recruit Count
472
Registration Number
NCT02861482
Locations
🇨🇳

Obstetrics and Gynechology Department of the 1st affiliated hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

Misoprostol+Oxytocin vs. Carbetocin in CS

Phase 2
Completed
Conditions
Cesarean Section
Interventions
First Posted Date
2016-06-01
Last Posted Date
2020-07-08
Lead Sponsor
Ain Shams University
Target Recruit Count
600
Registration Number
NCT02786992
Locations
🇪🇬

Ain Shams University Maternity Hospital, Cairo, Egypt

Effect of the Uterotonic Carbetocin on Acute Post Cesarean-Section Pain

Phase 4
Conditions
Cesarean Delivery
Interventions
First Posted Date
2015-12-30
Last Posted Date
2018-05-04
Lead Sponsor
Insel Gruppe AG, University Hospital Bern
Target Recruit Count
78
Registration Number
NCT02642263
Locations
🇨🇭

Dep. of Anesthesiology and Pain Medicine, Bern University Hospital, Bern, Switzerland

© Copyright 2025. All Rights Reserved by MedPath