Lanthanum carbonate

Generic Name
Lanthanum carbonate
Brand Names
Fosrenol
Drug Type
Small Molecule
Chemical Formula
C3La2O9
CAS Number
587-26-8
Unique Ingredient Identifier
0M78EU4V9H
Background

Lanthanum carbonate is a phosphate binder commonly used in clinical practice. It is marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is the largest of all pills filled in community pharmacies. Sometimes patients forget that Fosrenol is not swallowed whole, but instead should be chewed. This has led to severe choking. It is prescribed for t...

Indication

Used to reduce serum phosphate in patients with end stage renal disease (ESRD).

Associated Conditions
Hyperphosphataemia
Associated Therapies
-

Circadian Rhythm Modulation by Dietary Phosphorus in Chronic Kidney Disease

First Posted Date
2011-04-26
Last Posted Date
2014-02-11
Lead Sponsor
Geoffrey Block
Target Recruit Count
15
Registration Number
NCT01341678
Locations
🇺🇸

Denver Nephrologists, PC, Denver, Colorado, United States

Efficacy of Lanthanum Carbonate in Calciphylaxis

Phase 1
Completed
Conditions
First Posted Date
2011-02-04
Last Posted Date
2014-05-20
Lead Sponsor
University of Wisconsin, Madison
Target Recruit Count
12
Registration Number
NCT01289626
Locations
🇺🇸

University of Wisconsin Hospitals, Madison, Wisconsin, United States

Effect of Lanthanum Carbonate in Patients Previously Treated With Calcium-based Phosphate Binder Therapy

Completed
Conditions
First Posted Date
2010-05-26
Last Posted Date
2021-06-28
Lead Sponsor
Shire
Target Recruit Count
66
Registration Number
NCT01130831
Locations
🇩🇪

Dialyse am Treptower Park, Berlin, Germany

🇩🇪

Dialyse Alsfeld, Alsfeld, Germany

🇩🇪

Nephrologische Praxis Altötting-Burghausen, Altötting, Germany

and more 27 locations

Effects of Lanthanum Carbonate on FGF-23 in Subjects With Stage 3 CKD

First Posted Date
2010-05-21
Last Posted Date
2021-06-09
Lead Sponsor
Shire
Target Recruit Count
35
Registration Number
NCT01128179
Locations
🇫🇷

Dr Pablo Urena Torres, Saint Ouen, Paris, France

Comparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteers

First Posted Date
2009-04-03
Last Posted Date
2021-06-15
Lead Sponsor
Shire
Target Recruit Count
31
Registration Number
NCT00875017
Locations
🇺🇸

West Coast Clinical Trials, Cypress, California, United States

Fibroblast Growth Factor-23 (FGF23) Reduction in Predialysis Chronic Kidney Disease (CKD)

First Posted Date
2009-02-13
Last Posted Date
2013-06-07
Lead Sponsor
Myles Wolf
Target Recruit Count
43
Registration Number
NCT00843349
Locations
🇺🇸

University of Miami Hospital, Miami, Florida, United States

Phase III Study to Investigate the Safety and Efficacy of Fermagate and Lanthanum Carbonate

First Posted Date
2009-02-11
Last Posted Date
2010-10-19
Lead Sponsor
Ineos Healthcare Limited
Target Recruit Count
657
Registration Number
NCT00841126
Locations
🇨🇦

William Osler Health Centre, Brampton, Ontario, Canada

🇺🇸

Tidewater Kidney Specialists, Virginia Beach, Virginia, United States

🇦🇺

Royal Adelaide Hospital, Adelaide, South Australia, Australia

and more 102 locations

A Double Blind Randomized Placebo Trial of Maintenance of Normal Serum Phosphorus in CKD

First Posted Date
2008-11-05
Last Posted Date
2012-10-30
Lead Sponsor
Denver Nephrologists, P.C.
Target Recruit Count
148
Registration Number
NCT00785629
Locations
🇺🇸

Denver Nephrologists, PC, Denver, Colorado, United States

Long-term Effect of Lanthanum Carbonate on Bone

Completed
Conditions
Interventions
First Posted Date
2007-11-14
Last Posted Date
2021-07-13
Lead Sponsor
Shire
Target Recruit Count
34
Registration Number
NCT00557323
Locations
🇺🇸

Hypertension & Nephrology, Inc., Providence, Rhode Island, United States

🇬🇧

Addenbrooke's Hospital, Cambridge, United Kingdom

🇬🇧

St. Helier Hospital, Carshalton, United Kingdom

and more 13 locations

Conversion From Standard Phosphate Binder Therapy to Fosrenol® (Lanthanum Carbonate) in Chronic Kidney Disease Stage 5

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2007-03-27
Last Posted Date
2021-05-25
Lead Sponsor
Shire
Target Recruit Count
68
Registration Number
NCT00452478
Locations
🇧🇪

Ziekenhuis Zuid Oost Limburg, Genk, Belgium

🇩🇰

Frederica Sygehus, Fredericia, Denmark

🇩🇰

Sygehus Viborg, Viborg, Denmark

and more 11 locations
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