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Alanine

Generic Name
Alanine
Brand Names
Aminosyn II 7 %, Sulfite-free, Aminosyn-PF 7%, Clinimix 2.75/5, Clinimix E 2.75/5, Clinisol 15, Freamine 6.9, Freamine III 10, Hepatamine 8, Olimel, Periolimel, Plenamine, Premasol, Primene, Procalamine 3, Prosol, Travasol 10, Trophamine 10 %
Drug Type
Small Molecule
Chemical Formula
C3H7NO2
CAS Number
56-41-7
Unique Ingredient Identifier
OF5P57N2ZX
Background

Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.

Indication

Used for protein synthesis.

Associated Therapies
Amino acid supplementation

The Separate and Combined Glucagonotropic Effects of Glucose-dependent Insulinotropic Polypeptide and Alanine in Subjects with and Without Type 1 Diabetes

Not Applicable
Conditions
Type 1 Diabetes
Interventions
Drug: Glucose-dependent Insulinotropic Polypeptide (GIP)
Drug: Saline (NaCl 0,9 %) (placebo)
First Posted Date
2025-03-18
Last Posted Date
2025-03-18
Lead Sponsor
Asger Lund, MD
Target Recruit Count
10
Registration Number
NCT06881472
Locations
🇩🇰

Gentofte Hospital, Hellerup, Denmark

The Glucagonotropic Effects of Glucose-dependent Insulinotropic Polypeptide and Alanine in Healthy Individuals

Phase 1
Recruiting
Conditions
Effect of iv Administration of GIP and Alanine
Interventions
Other: Placebo (saline)
Drug: GIP
First Posted Date
2024-05-17
Last Posted Date
2024-05-17
Lead Sponsor
University Hospital, Gentofte, Copenhagen
Target Recruit Count
10
Registration Number
NCT06419686
Locations
🇩🇰

Center for Clinical Metabolic Research, Gentofte Hospital, Hellerup, Capital Region, Denmark

Effects of Alanine in Patients With Nonalcoholic Steatohepatitis

Not Applicable
Completed
Conditions
Nonalcoholic Steatohepatitis
Interventions
First Posted Date
2008-01-07
Last Posted Date
2012-10-11
Lead Sponsor
Keith D Lindor, M.D.
Target Recruit Count
9
Registration Number
NCT00586885
Locations
🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

Gluconeogenesis in Very Low Birth Weight Infants Who Are Receiving Nutrition By Intravenous Infusion

Not Applicable
Conditions
Infant, Low Birth Weight
Hyperglycemia
First Posted Date
2000-06-05
Last Posted Date
2005-06-24
Lead Sponsor
National Center for Research Resources (NCRR)
Target Recruit Count
96
Registration Number
NCT00005889
Locations
🇺🇸

Baylor College of Medicine, Houston, Texas, United States

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