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Isocarboxazid

Generic Name
Isocarboxazid
Brand Names
Marplan
Drug Type
Small Molecule
Chemical Formula
C12H13N3O2
CAS Number
59-63-2
Unique Ingredient Identifier
34237V843T

Overview

Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor. It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders. It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.

Background

Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor. It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders. It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription drug on July 1st, 1959.

Indication

Isocarboxazid is indicated for the treatment of the enduring and debilitating symptoms of depression that have not responded to other antidepressant drugs. Depression is a common but serious mood disorder. The patient will present changes in its feelings, thoughts, and ability to handle everyday activities. For a mood disorder to be considered as depression, the symptoms should be present for at least two weeks.

Associated Conditions

  • Depression

Clinical Trials

FDA Approved Products

Marplan
Manufacturer:MediLink A/S
Route:ORAL
Strength:10 mg in 1 1
Approved: 2018/12/20
NDC:72604-032
Marplan
Manufacturer:Validus Pharmaceuticals LLC
Route:ORAL
Strength:10 mg in 1 1
Approved: 2023/07/17
NDC:30698-032

Singapore Approved Products

No Singapore products found for this drug

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