MedPath

JMT-103

Generic Name
JMT-103

The Efficacy and Safety of Narlumosbart in Combination with Stereotactic Body Radiation Therapy to Improve the Efficacy of First-line Chemotherapy Combined with Immunotherapy in Patients with Bone Metastases from Advanced Non-small Cell Lung Cancer

Phase 2
Not yet recruiting
Conditions
NSCLC
Stereotactic Body Radiation Therapy (SBRT)
Immunotherapy
Interventions
First Posted Date
2025-03-25
Last Posted Date
2025-03-27
Lead Sponsor
Fudan University
Target Recruit Count
27
Registration Number
NCT06738160

Narlumosbart Compared With Denosumab in Patients With Multiple Myeloma Bone Disease

Phase 3
Not yet recruiting
Conditions
Multiple Myeloma
Bone Diseases
Interventions
First Posted Date
2024-03-18
Last Posted Date
2024-03-18
Lead Sponsor
RenJi Hospital
Target Recruit Count
478
Registration Number
NCT06314698

A Study to Assess the Prevention of Bone-related Events in Patients With Bone Metastases From Malignant Solid Tumors Treated With JMT103 Compared to Zoledronic Acid

Phase 3
Not yet recruiting
Conditions
Imaging Examination Shows at Least One Site With Bone Metastases From Soild Tumors
Interventions
First Posted Date
2024-01-24
Last Posted Date
2024-01-24
Lead Sponsor
Shanghai JMT-Bio Inc.
Target Recruit Count
1360
Registration Number
NCT06221072

A Study to Evaluate the Efficacy and Safety of Narlumosbart (JMT103) in Patients With Giant Cell Tumor of Bone

Phase 3
Not yet recruiting
Conditions
Giant Cell Tumor of Bone
Interventions
First Posted Date
2023-04-14
Last Posted Date
2023-04-19
Lead Sponsor
Shanghai JMT-Bio Inc.
Target Recruit Count
146
Registration Number
NCT05813665
Locations
🇨🇳

Beijing Ji Shui Tan Hospital, Beijing, Beijing, China

Efficacy and Safety of JMT103 in the Treatment of Glucocorticoid Induced Osteoporosis

Phase 2
Conditions
Glucocorticoid Induced Osteoporosis
Interventions
First Posted Date
2022-05-31
Last Posted Date
2022-05-31
Lead Sponsor
Shanghai JMT-Bio Inc.
Target Recruit Count
231
Registration Number
NCT05397938
Locations
🇨🇳

Peking University First Hospital, Beijing, Beijing, China

Efficacy and Safety of JMT103 in the Treatment of Postmenopausal Women With Osteoporosis

Phase 2
Conditions
Postmenopausal Osteoporosis
Interventions
First Posted Date
2022-03-14
Last Posted Date
2022-07-18
Lead Sponsor
Shanghai JMT-Bio Inc.
Target Recruit Count
200
Registration Number
NCT05278338
Locations
🇨🇳

The Second Hospital of Jilin University, Changchun, Jilin, China

A Clinical Trial to Assess the Efficacy and Safety of JMT103 in Patients With Refractory HCM

Phase 1
Conditions
Hypercalcemia of Malignancy
Interventions
First Posted Date
2019-12-13
Last Posted Date
2019-12-13
Lead Sponsor
Shanghai JMT-Bio Inc.
Target Recruit Count
17
Registration Number
NCT04198480
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