Berberine
- Generic Name
- Berberine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C20H18NO4
- CAS Number
- 2086-83-1
- Unique Ingredient Identifier
- 0I8Y3P32UF
- Background
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
- Indication
主要用于志贺菌属、霍乱弧菌等敏感病原菌所致的胃肠炎、细菌性痢疾等肠道感染。
外用用于治疗敏感细菌引起的宫颈糜烂。
- Associated Conditions
- -
- Associated Therapies
- -
Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.
- Conditions
- Interventions
- First Posted Date
- 2024-09-19
- Last Posted Date
- 2024-09-19
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 548
- Registration Number
- NCT06603688
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xian, Shaanxi, China
Study on The Efficacy and Safety of Vonoprazan-containing Berberine Triple Therapy in Helicobacter Pylori First-Line Eradication
- Conditions
- Interventions
- First Posted Date
- 2024-07-23
- Last Posted Date
- 2024-07-23
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 558
- Registration Number
- NCT06514274
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xi'an, Shaanxi, China
Cardiovascular Diseases and Diabetes Prevention Programme in Metabolic Syndrome (CDPP)
- Conditions
- Interventions
- First Posted Date
- 2021-11-03
- Last Posted Date
- 2021-11-03
- Lead Sponsor
- Tang Yida
- Target Recruit Count
- 5200
- Registration Number
- NCT05105321
- Locations
- 🇨🇳
Peking University Third Hospital, Beijing, Beijing, China
Study on The Efficacy and Safety of Berberine-containing Triple Therapy in Helicobacter Pylori First-Line Eradication
- Conditions
- Interventions
- First Posted Date
- 2021-08-20
- Last Posted Date
- 2023-01-31
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 300
- Registration Number
- NCT05014334
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xi'an, Shaanxi, China
Effect of Berberine on Metabolic Syndrome, Efficacy and Safety in Combination With Antiretroviral Therapy in PLWH.
- Conditions
- Interventions
- First Posted Date
- 2021-04-26
- Last Posted Date
- 2021-04-26
- Lead Sponsor
- Hospital Civil de Guadalajara
- Target Recruit Count
- 40
- Registration Number
- NCT04860063
Helicobacter Pylori Eradication With Berberine Plus Amoxicillin Triple Therapy Versus Bismuth-containing Quadruple Therapy
- Conditions
- Interventions
- First Posted Date
- 2021-01-06
- Last Posted Date
- 2023-01-31
- Lead Sponsor
- Xijing Hospital of Digestive Diseases
- Target Recruit Count
- 524
- Registration Number
- NCT04697186
- Locations
- 🇨🇳
Xijing Hosipital of Digestive Disease, Xi'an, Shaanxi, China
Effects Of Berberine Plus Inulin On Diabetes Care in Patients With LADA
- Conditions
- Interventions
- First Posted Date
- 2021-01-06
- Last Posted Date
- 2022-02-25
- Target Recruit Count
- 240
- Registration Number
- NCT04698330
- Locations
- 🇨🇳
Institute of Metabolism and Endocrinology, Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Endoscopic and Microbiological Assessment of the Effect of Carvedilol Combined With Berberine on GOV in Cirrhosis
- Conditions
- Interventions
- First Posted Date
- 2020-09-10
- Last Posted Date
- 2021-10-25
- Lead Sponsor
- Tianjin Second People's Hospital
- Target Recruit Count
- 288
- Registration Number
- NCT04543643
- Locations
- 🇨🇳
Tianjin Second People's Hospital, Tianjin, Tianjin, China
The Effect of Berberine on Intestinal Function and Inflammatory Mediators in Severe Patients With Covid-19
- First Posted Date
- 2020-07-21
- Last Posted Date
- 2020-07-21
- Lead Sponsor
- Chinese Medical Association
- Target Recruit Count
- 76
- Registration Number
- NCT04479202
- Locations
- 🇨🇳
Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China
Effect of Berberine for Endothelial Function and Intestinal Microflora in Patients With Coronary Artery Disease
- First Posted Date
- 2020-06-16
- Last Posted Date
- 2020-06-16
- Lead Sponsor
- Peking Union Medical College Hospital
- Target Recruit Count
- 24
- Registration Number
- NCT04434365
- Locations
- 🇨🇳
Peking Union Medical College Hospital, Beijing, Beijing, China
Drug Development Updates
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