Overview
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Background
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Indication
主要用于志贺菌属、霍乱弧菌等敏感病原菌所致的胃肠炎、细菌性痢疾等肠道感染。 外用用于治疗敏感细菌引起的宫颈糜烂。
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2025/01/20 | Phase 2 | ENROLLING_BY_INVITATION | |||
2024/10/07 | N/A | Recruiting | Shanghai Jiao Tong University School of Medicine | ||
2024/09/19 | Phase 4 | Recruiting | Xijing Hospital of Digestive Diseases | ||
2024/07/23 | Phase 4 | Completed | Xijing Hospital of Digestive Diseases | ||
2023/07/17 | Early Phase 1 | Completed | Beijing Tongren Hospital | ||
2023/03/01 | Phase 4 | Not yet recruiting | China National Center for Cardiovascular Diseases | ||
2023/02/09 | Not Applicable | Recruiting | Yu Chen | ||
2022/12/13 | Phase 4 | Completed | China National Center for Cardiovascular Diseases | ||
2021/11/03 | Phase 4 | Not yet recruiting | Tang Yida | ||
2021/08/20 | Phase 4 | Completed | Xijing Hospital of Digestive Diseases |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| No FDA approvals found for this drug. | |||||
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| Berberine Hydrochloride Capsules | 国药准字H20023402 | 化学药品 | 胶囊剂 | 11/27/2020 | |
| Berberine Hydrochloride Capsules | 国药准字H53021319 | 化学药品 | 胶囊剂 | 6/22/2020 | |
| Berberine Hydrochloride Capsules | 国药准字H20045876 | 化学药品 | 胶囊剂 | 9/2/2020 | |
| Berberine Hydrochloride Capsules | 国药准字H50020837 | 化学药品 | 胶囊剂 | 7/17/2020 | |
| Berberine Hydrochloride Capsules | 国药准字H44023970 | 化学药品 | 胶囊剂 | 2/12/2020 | |
| Berberine Hydrochloride Capsules | 国药准字H51020101 | 化学药品 | 胶囊剂 | 12/2/2019 | |
| Berberine Hydrochloride Capsules | 国药准字H34021050 | 化学药品 | 胶囊剂 | 6/2/2020 | |
| Berberine Hydrochloride Capsules | 国药准字H50020485 | 化学药品 | 胶囊剂 | 4/9/2020 | |
| Berberine Hydrochloride Capsules | 国药准字H45020640 | 化学药品 | 胶囊剂 | 8/19/2020 | |
| Berberine Hydrochloride Tablets | 国药准字H41023247 | 化学药品 | 片剂 | 7/6/2020 |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| MURINE RELIEF berberine chloride 0.26mg/mL eye drops bottle | 29660 | Medicine | A | 10/21/1991 |