Dienogest

Generic Name
Dienogest
Brand Names
Natazia, Visanne
Drug Type
Small Molecule
Chemical Formula
C20H25NO2
CAS Number
65928-58-7
Unique Ingredient Identifier
46M3EV8HHE
Background

Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is ...

Indication

Indicated for use as the treatment of endometriosis alone and as a contraceptive in combination with ethinylestradiol.

Associated Conditions
Hypermenorrhea, Pain
Associated Therapies
Contraception, Oral Contraceptives

Trial Comparing Preoperative Dienogest Therapy Followed by Surgery vs. Upfront Surgery to Save Ovarian Reserve in Young Women With Ovarian Endometrioma

First Posted Date
2016-04-05
Last Posted Date
2017-10-31
Lead Sponsor
Seoul National University Hospital
Registration Number
NCT02728245
Locations
🇰🇷

Seoul National University Bundang Hospital, Seongnam Si, Gyeonggi Do, Korea, Republic of

Impact vs. Dienogest: A Combined Oral Contraceptive in the Size of Endometriomas

Phase 2
Suspended
Conditions
Interventions
First Posted Date
2015-11-06
Last Posted Date
2016-11-22
Lead Sponsor
Fundación Santa Fe de Bogota
Target Recruit Count
50
Registration Number
NCT02599077
Locations
🇨🇴

Fundación Santa Fe de Bogota, Bogota, Cundinamarca, Colombia

Endometrial Preparation Before Operative Hysteroscopy in Premenopausal Women

First Posted Date
2015-05-12
Last Posted Date
2016-03-09
Lead Sponsor
University of Cagliari
Target Recruit Count
50
Registration Number
NCT02440750

Dienogest Versus Luteal Phase Fluoxetine in the Management of Premenstrual Syndrome

First Posted Date
2015-04-28
Last Posted Date
2020-12-01
Lead Sponsor
Cairo University
Target Recruit Count
210
Registration Number
NCT02427334
Locations
🇪🇬

Cairo university hospitals, Cairo, Egypt

Comparing the Use of Dienogest and Combined Oral Contraceptive Pills (Microgynon) to Reduce the Risk of Recurrence of Endometriotic Cyst After Conservative Surgery

Phase 4
Conditions
Interventions
First Posted Date
2015-03-11
Last Posted Date
2015-04-29
Lead Sponsor
The University of Hong Kong
Target Recruit Count
144
Registration Number
NCT02385448
Locations
🇭🇰

Queen Mary Hospital, Hong Kong, Hong Kong

Synthetic vs Natural Estrogen in Combined Oral Contraception

First Posted Date
2015-02-02
Last Posted Date
2023-06-22
Lead Sponsor
Helsinki University Central Hospital
Target Recruit Count
59
Registration Number
NCT02352090
Locations
🇫🇮

Helsinki University Central Hospital, Kätilöopisto Maternity Hospital, Helsinki, Finland

🇫🇮

Oulu University Hospital, Department of Gynecology and Obstetrics, Oulu, Finland

Study of the Efficacy of Dienogest in the Treatment of Uterine Leiomyomas When Compared to Desogestrel and Goserelin

First Posted Date
2012-11-30
Last Posted Date
2020-08-13
Lead Sponsor
University of Sao Paulo
Target Recruit Count
14
Registration Number
NCT01738724

Comparative Study of BAY86-5300 With an Extended Flexible Regimen for Endometriosis

First Posted Date
2012-10-02
Last Posted Date
2016-02-18
Lead Sponsor
Bayer
Target Recruit Count
312
Registration Number
NCT01697111
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