Tafluprost

Generic Name
Tafluprost
Brand Names
Zioptan
Drug Type
Small Molecule
Chemical Formula
C25H34F2O5
CAS Number
209860-87-7
Unique Ingredient Identifier
1O6WQ6T7G3
Background

A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.

Indication

Tafluprost is indicated for reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Associated Conditions
Increased Intra Ocular Pressure (IOP), Ocular Hypertension
Associated Therapies
-

Prospective, Single Center Switching Study of 0.0015% Tafluprost Ophthalmic Solution in Primary Open-angle Glaucoma and Ocular Hypertension Patients With Corneal Disorders (Switching From 0.005% Latanoprost Ophthalmic Solution)

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2021-02-04
Last Posted Date
2021-02-04
Lead Sponsor
Santen Pharmaceutical (Taiwan) Co., LTD
Target Recruit Count
1
Registration Number
NCT04737928
Locations
🇨🇳

Chi Mei Hospital Liouying Branch, Tainan, Taiwan

24-hour Efficacy and Ocular Surface With Talfuprost and Triple Combined Therapy

First Posted Date
2016-06-16
Last Posted Date
2020-12-17
Lead Sponsor
Aristotle University Of Thessaloniki
Target Recruit Count
43
Registration Number
NCT02802137

Switching From Preserved to Preserved-free Treatments for Glaucoma.

Phase 3
Conditions
Interventions
First Posted Date
2011-09-14
Last Posted Date
2014-05-16
Lead Sponsor
Paolo Fogagnolo
Target Recruit Count
40
Registration Number
NCT01433900
Locations
🇮🇹

San Paolo Hospital, Milano, Italy

Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost to Preservative Free Tafluprost Eye Drops

Phase 3
Completed
Conditions
Interventions
First Posted Date
2010-03-16
Last Posted Date
2013-05-31
Lead Sponsor
Santen Oy
Target Recruit Count
185
Registration Number
NCT01087671

Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Drops

Phase 3
Completed
Conditions
Interventions
First Posted Date
2008-01-17
Last Posted Date
2009-01-12
Lead Sponsor
Santen Oy
Target Recruit Count
150
Registration Number
NCT00596791
Locations
🇫🇮

Finn-Medi Research Oy, Tampere, Finland

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